Effect of allogeneic hematopoietic stem cell transplantation on sickle cell disease‐related organ complications: a systematic review and meta‐analysis

E Dovern, M Aydin, MR DeBaun… - American Journal of …, 2024 - Wiley Online Library
Sickle cell disease (SCD)‐related organ complications are a major cause of morbidity and
mortality in patients with SCD. We sought to assess whether hematopoietic stem cell …

[HTML][HTML] Treatment and prevention of pathological mitochondrial dysfunction in retinal degeneration and in photoreceptor injury

WH Moos, DV Faller, IP Glavas, DN Harpp… - Biochemical …, 2022 - Elsevier
Pathological deterioration of mitochondrial function is increasingly linked with multiple
degenerative illnesses as a mediator of a wide range of neurologic and age-related chronic …

Risk factors associated with sickle cell retinopathy: findings from the Cooperative Study of Sickle Cell Disease

M Nawaiseh, A Roto, Y Nawaiseh, M Salameh… - International Journal of …, 2022 - Springer
Background Sickle cell retinopathy (SCR) is one of the most important ocular manifestations
of sickle cell disease (SCD). This study aims to assess the prevalence of SCR in SCD …

Comparison of line‐field confocal optical coherence tomography images with histological sections: validation of a new method for in vivo and non‐invasive …

M Pedrazzani, J Breugnot… - Skin Research and …, 2020 - Wiley Online Library
Background Line‐field confocal optical coherence tomography (LC‐OCT) is an imaging
technique providing “optical biopsies” of the skin in real time and non‐invasively. At a center …

Longitudinal assessment of macular thickness and microvascular changes in children with sickle cell disease

S Hoyek, C Lemire, O Halawa… - Ophthalmology …, 2024 - Elsevier
Purpose To longitudinally assess macular thickness and microvascular changes in children
with sickle cell disease (SCD). Design A retrospective consecutive series. Subjects Children …

[HTML][HTML] Do we store packed red blood cells under “Quasi-Diabetic” conditions?

L Livshits, G Barshtein, D Arbell, A Gural, C Levin… - Biomolecules, 2021 - mdpi.com
Red blood cell (RBC) transfusion is one of the most common therapeutic procedures in
modern medicine. Although frequently lifesaving, it often has deleterious side effects. RBC …

Proliferative sickle cell retinopathy: outcomes of vitreoretinal surgery

LJ Rohowetz, S Panneerselvam, BK Williams Jr… - Ophthalmology …, 2024 - Elsevier
Purpose To report the clinical presentation and outcomes in patients who underwent surgery
for proliferative sickle cell retinopathy (PSCR). Design Retrospective, consecutive case …

Systemic medications for sickle cell disease and potential applications for sickle cell retinopathy

AK Garg, AW Scott - Current opinion in ophthalmology, 2024 - journals.lww.com
Hydroxyurea has been a mainstay of systemic management of SCD with prior work
suggesting its ability to reduce the likelihood of develo** retinopathy. There are several …

Sickle cell maculopathy: microstructural analysis using OCTA and identification of genetic, systemic, and biological risk factors

S Fares, S Hajjar, M Romana, P Connes… - American Journal of …, 2021 - Elsevier
Purpose To identify genetic, systemic, and biological factors associated with the occurrence
of sickle cell maculopathy (SCM). To evaluate microvascular macular alterations using …

Evaluation of peripheral blood inflammatory biomarkers in sickle cell disease with and without retinopathy

Ö Özer, L Doğan, Z Baysal, H Basir, AT Çıftçı… - Graefe's Archive for …, 2024 - Springer
Background The aim of this study was to evaluate the clinical significance of blood-cell
associated inflammation markers in patients with sickle cell disease (SCD) and sickle cell …