Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?
With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …
placing a growing burden on individuals and the whole society. However, individual rates of …
Predicting age using neuroimaging: innovative brain ageing biomarkers
The brain changes as we age and these changes are associated with functional
deterioration and neurodegenerative disease. It is vital that we better understand individual …
deterioration and neurodegenerative disease. It is vital that we better understand individual …
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …
Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations
Brain clocks, which quantify discrepancies between brain age and chronological age, hold
promise for understanding brain health and disease. However, the impact of diversity …
promise for understanding brain health and disease. However, the impact of diversity …
Brain aging mechanisms with mechanical manifestations
Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
Development of the cerebral cortex across adolescence: a multisample study of inter-related longitudinal changes in cortical volume, surface area, and thickness
Before we can assess and interpret how developmental changes in human brain structure
relate to cognition, affect, and motivation, and how these processes are perturbed in clinical …
relate to cognition, affect, and motivation, and how these processes are perturbed in clinical …
Predicting brain-age from multimodal imaging data captures cognitive impairment
The disparity between the chronological age of an individual and their brain-age measured
based on biological information has the potential to offer clinically relevant biomarkers of …
based on biological information has the potential to offer clinically relevant biomarkers of …
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years
Delineating the association of age and cortical thickness in healthy individuals is critical
given the association of cortical thickness with cognition and behavior. Previous research …
given the association of cortical thickness with cognition and behavior. Previous research …
The aging navigational system
The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …
functionally distinct cell types such as place and grid cells, combined with an extensive body …
Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome
How does human brain structure mature during adolescence? We used MRI to measure
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …