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Role of PI3K in the progression and regression of atherosclerosis
Y Zhao, Y Qian, Z Sun, X Shen, Y Cai, L Li… - Frontiers in …, 2021 - frontiersin.org
Phosphatidylinositol 3 kinase (PI3K) is a key molecule in the initiation of signal transduction
pathways after the binding of extracellular signals to cell surface receptors. An intracellular …
pathways after the binding of extracellular signals to cell surface receptors. An intracellular …
Platycodin D ameliorates cognitive impairment in type 2 diabetes mellitus mice via regulating PI3K/Akt/GSK3β signaling pathway
Y Lu, L **e, M Qi, S Ren, Y Wang, J Hu… - Journal of Agricultural …, 2024 - ACS Publications
Objectives: The aim of this study was to investigate the ameliorative effect of platycodin D
(PD) on cognitive dysfunction in type 2 diabetes mellitus (T2DM) and its potential molecular …
(PD) on cognitive dysfunction in type 2 diabetes mellitus (T2DM) and its potential molecular …
Combination of ADAM17 knockdown with eplerenone is more effective than single therapy in ameliorating diabetic cardiomyopathy
L **e, D Zang, J Yang, F Xue, W Sui… - Frontiers in …, 2024 - frontiersin.org
Background The renin-angiotensin-aldosterone system (RAAS) members, especially Ang II
and aldosterone, play key roles in the pathogenesis of diabetic cardiomyopathy (DCM) …
and aldosterone, play key roles in the pathogenesis of diabetic cardiomyopathy (DCM) …
Rg1 protects H9C2 cells from high glucose‐/palmitate‐induced injury via activation of AKT/GSK‐3β/Nrf2 pathway
H Yu, J Zhen, Y Yang, J Du, J Leng… - Journal of Cellular and …, 2020 - Wiley Online Library
Our previous studies have assessed ginsenoside Rg1 (Rg1)‐mediated protection in a type 1
diabetes rat model. To uncover the mechanism through which Rg1 protects against cardiac …
diabetes rat model. To uncover the mechanism through which Rg1 protects against cardiac …
Rosuvastatin and low‐dose carvedilol combination protects against isoprenaline‐induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO‐1 signalling
SA Baraka, MF Tolba, DA Elsherbini… - Clinical and …, 2021 - Wiley Online Library
Rosuvastatin has been shown to activate PI3K/Akt/Nrf2/HO‐1 pathway, which promotes cell
survival in the myocardium. This study investigated the therapeutic benefit of adding …
survival in the myocardium. This study investigated the therapeutic benefit of adding …
[HTML][HTML] Irisin enhances angiogenesis of mesenchymal stem cells to promote cardiac function in myocardial infarction via Pi3k/Akt activation
F Yang, Z Wang, B Li, Y He, F Du… - … Journal of Stem …, 2021 - synapse.koreamed.org
Methods and Results In vivo, irisin-treated BMSCs (BMSCs+ irisin) were transplanted into an
MI mouse model. On day 28 post-MI, blood vessel markers were detected, and cardiac …
MI mouse model. On day 28 post-MI, blood vessel markers were detected, and cardiac …
Circular RNA Involved in the Protective Effect of Malva sylvestris L. on Myocardial Ischemic/Re-Perfused Injury
Y **ao, DB Oumarou, S Wang, Y Liu - Frontiers in pharmacology, 2020 - frontiersin.org
Ischemic heart disease has become a major health challenge worldwide. Malva sylvestris
L.(MS) is a traditional herbal medicine with anti-inflammatory properties and have been …
L.(MS) is a traditional herbal medicine with anti-inflammatory properties and have been …
[PDF][PDF] Protective effect of MAPK signaling pathway mediated by ITGB3 gene silencing on myocardial ischemia-reperfusion injury in mice and its mechanism.
MC Wang, D Wang, YH Lu, ZH Li… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: To explore the effect of integrin β3 (ITGB3) gene silencing mediated mitogen-
activated protein kinase (MAPK) signaling pathway on myocardial ischemia-reperfusion …
activated protein kinase (MAPK) signaling pathway on myocardial ischemia-reperfusion …
25-OH-PPD inhibits hypertrophy on diabetic cardiomyopathy via the PI3k/Akt/GSK-3β signaling pathway
X Liu, F Song, C Liu, Y Zhang - Experimental and …, 2020 - spandidos-publications.com
The present study investigated the inhibitory effects and the associated mechanism of the
compound 25-OH-PPD (PPD) on cardiac hypertrophy, fibrosis and inflammation. The …
compound 25-OH-PPD (PPD) on cardiac hypertrophy, fibrosis and inflammation. The …
La eplerona eplerona revierte la inflamación testicular mejorando la calidad espermática epididimal inducida por estrés crónico variable en ratas jóvenes adultas
O Pérez, T Guadalupe - 2024 - repositorio.uatx.mx
La infertilidad es la incapacidad de procrear cuando una pareja se somete a actividad
sexual constante sin el uso de anticonceptivos, y sin el éxito reproductivo. Los casos de …
sexual constante sin el uso de anticonceptivos, y sin el éxito reproductivo. Los casos de …