Plasmodium sporozoites are deposited in the skin of their vertebrate hosts through the bite
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

Many protozoans of the phylum Apicomplexa are invasive parasites that exhibit a substrate-
dependent gliding motility. Plasmodium (malaria) sporozoites, the stage of the parasite that …

Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the
mammalian liver. The sporozoite's major surface protein, circumsporozoite protein (CSP), is …

Malaria caused by Plasmodium falciparum remains a major public health threat, especially
among children and pregnant women in Africa. An effective malaria vaccine would be a …

A large array of glycoproteins, glycolipids, and proteoglycans decorate the surfaces of
animal cells. These glycoconjugates mediate many fundamental cellular processes …

Plasmodium sporozoite invasion of liver cells has been an extremely elusive event to study.
In the prevailing model, sporozoites enter the liver by passing through Kupffer cells, but this …

Peptide dendrimers are radial or wedge-like branched macromolecules consisting of a
peptidyl branching core and/or covalently attached surface functional units. The multimeric …

Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …

Human infections with Plasmodium falciparum may result in severe forms of malaria. The
widespread and rapid development of drug resistance in P. falciparum and the resistance of …