The dual role of microglia in intracerebral hemorrhage

Y Sun, W Sun, J Liu, B Zhang, L Zheng… - Behavioural Brain …, 2024 - Elsevier
Intracerebral hemorrhage has the characteristics of high morbidity, disability and mortality,
which has caused a heavy burden to families and society. Microglia are resident immune …

[HTML][HTML] Advances in understanding and exploiting Siglec–glycan interactions

Z Jame-Chenarboo, TE Gray, MS Macauley - Current Opinion in Chemical …, 2024 - Elsevier
Sialic-acid-binding immunoglobulin-type lectins (Siglecs) are a family of cell-surface
immunomodulatory receptors that recognize sialic-acid-containing glycans. The majority of …

CpG and Rutin Co‐Loaded DNA Tetrahedra for Targeted Therapy of Intracerebral Hemorrhage: Synergistic Hematoma Clearance and Neuroinflammation Inhibition

J Wang, N **e, S Lu, B **ao, Y Ou, Q Li… - Advanced Functional …, 2024 - Wiley Online Library
Intracerebral hemorrhage (ICH) presents a formidable challenge due to its high mortality
and disability rates, primarily attributed to cerebral hematoma formation and ensuing …

Pterostilbene improves neurological dysfunction and neuroinflammation after ischaemic stroke via HDAC3/Nrf1-mediated microglial activation

Y Chen, W He, J Qiu, Y Luo, C Jiang, F Zhao… - Cellular & Molecular …, 2024 - Springer
Background Stroke is a type of acute brain damage that can lead to a series of serious
public health challenges. Demonstrating the molecular mechanism of stroke-related neural …

CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder

W Zhang, Y Han, H Huang, Y Su, H Ren, C Qi… - Journal of …, 2024 - Springer
Background Neuromyelitis optica spectrum disorder (NMOSD) is an autoantibody-triggered
central nervous system (CNS) demyelinating disease that primarily affects the spinal cord …

Extracellular Vesicles From Bone Marrow‐Derived Macrophages Enriched in ARG1 Enhance Microglial Phagocytosis and Haematoma Clearance Following …

L Hu, Z Chen, J Lu, S Jiang, H Lin… - Journal of …, 2025 - Wiley Online Library
Microglial phagocytosis of haematomas is crucial for neural functional recovery following
intracerebral haemorrhage (ICH), a process regulated by various factors from within and …

Condensed tannin improves growth and alleviates intestinal inflammation of juvenile largemouth bass (Micropterus salmoides) fed with high cottonseed protein …

M Yang, D Jiang, W Lai, K Chen, S Xu, R Yu… - International Journal of …, 2024 - Elsevier
The objective of this study was to examine the potential of condensed tannin (CT) in
mitigating the adverse effects on growth and intestinal health induced by high cottonseed …

[HTML][HTML] Siglecs-mediated immune regulation in neurological disorders

H Tu, L Yuan, B Ni, Y Lin, K Wang - Pharmacological Research, 2024 - Elsevier
The surfaces of various immune cells are rich in glycan chains, including the sialic-acid-
binding immunoglobulin-like lectins (Siglecs) family. As an emerging glyco-immune …

[HTML][HTML] Roles for Siglec-glycan interactions in regulating immune cells

SY Lin, EN Schmidt, K Takahashi-Yamashiro… - Seminars in …, 2025 - Elsevier
Cell surface complex carbohydrates, known as glycans, are positioned to be the first point of
contact between two cells. Indeed, interactions between glycans with glycan-binding can …

[HTML][HTML] Targeting macrophages in cancer immunotherapy: Frontiers and challenges

Y Liu, H Tan, J Dai, J Lin, K Zhao, H Hu… - Journal of Advanced …, 2025 - Elsevier
Background Cancer immunotherapy has emerged as a groundbreaking approach in cancer
treatment, primarily realized through the manipulation of immune cells, notably T cell …