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Exploring the bone marrow micro environment in thalassemia patients: potential therapeutic alternatives
Z Li, X Yao, J Zhang, J Yang, J Ni, Y Wang - Frontiers in Immunology, 2024 - frontiersin.org
Genetic mutations in the β-globin gene lead to a decrease or removal of the β-globin chain,
causing the build-up of unstable alpha-hemoglobin. This condition is referred to as beta …
causing the build-up of unstable alpha-hemoglobin. This condition is referred to as beta …
Placenta-derived extracellular vesicles in pregnancy complications and prospects on a liquid biopsy for hemoglobin Bart's disease
Extracellular vesicles (EVs) are nano-scaled vesicles released from all cell types into
extracellular fluids and specifically contain signature molecules of the original cells and …
extracellular fluids and specifically contain signature molecules of the original cells and …
Associations of maternal and placental extracellular vesicle miRNA with preeclampsia
A Aharon, A Rebibo-Sabbah, RS Ahmad… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Gestational vascular complications (GVCs), including gestational hypertension
and preeclampsia, are leading causes of maternal morbidity and mortality. Elevated levels of …
and preeclampsia, are leading causes of maternal morbidity and mortality. Elevated levels of …
Post-transcriptional regulation of erythropoiesis
Y Li, H Zhang, B Hu, P Wang, W Wang, J Liu - Blood Science, 2023 - journals.lww.com
Erythropoiesis is a complex, precise, and lifelong process that is essential for maintaining
normal body functions. Its strict regulation is necessary to prevent a variety of blood …
normal body functions. Its strict regulation is necessary to prevent a variety of blood …
Host and microbiota derived extracellular vesicles: Crucial players in iron homeostasis
Iron is a double-edged sword. It is vital for all that's living, yet its deficiency or overload can
be fatal. In humans, iron homeostasis is tightly regulated at both cellular and systemic levels …
be fatal. In humans, iron homeostasis is tightly regulated at both cellular and systemic levels …
Depletion of miR-144/451 alleviates anemia in β-thalassemic mice
Hospital, Nan**g Medical University, Nan**g, China β-thalassemia is a hereditary disease
caused by the β-globin gene mutations. Blood transfusion, 1, 2 stem cell transplantation, 3, 4 …
caused by the β-globin gene mutations. Blood transfusion, 1, 2 stem cell transplantation, 3, 4 …
[HTML][HTML] The role of extracellular vesicles on the occurrence of clinical complications in β-thalassemia
HIGHLIGHTS•Extracellular vesicles cause a hypercoagulable state in patients with β-
thalassemia.•Extracellular vesicles can increase iron overload in patients with β …
thalassemia.•Extracellular vesicles can increase iron overload in patients with β …
An update on recent studies of extracellular vesicles and their role in hypercoagulability in thalassemia
P Klaihmon, K Pattanapanyasat… - Biomedical …, 2023 - spandidos-publications.com
Thromboembolic events are a significant clinical concern in thalassemia and
hemoglobinopathies, highlighting the need for new strategies to treat and detect these …
hemoglobinopathies, highlighting the need for new strategies to treat and detect these …
Clinical implications of miRNAs in erythropoiesis, anemia, and other hematological disorders
Erythropoiesis is regulated by the differential expression of many genes. Besides being
transcriptionally regulated, these genes are also with the oath of epigenetic regulation by the …
transcriptionally regulated, these genes are also with the oath of epigenetic regulation by the …
[HTML][HTML] Potential Use of MicroRNA Technology in Thalassemia Therapy
Thalassemia encompasses a group of inherited hemoglobin disorders characterized by
reduced or absent production of the α-or β-globin chains, leading to anemia and other …
reduced or absent production of the α-or β-globin chains, leading to anemia and other …