Decoding the brain: From neural representations to mechanistic models
A central principle in neuroscience is that neurons within the brain act in concert to produce
perception, cognition, and adaptive behavior. Neurons are organized into specialized brain …
perception, cognition, and adaptive behavior. Neurons are organized into specialized brain …
Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease
The degeneration of mesencephalic dopaminergic neurons that innervate the basal ganglia
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …
Preparatory activity and the expansive null-space
The study of the cortical control of movement experienced a conceptual shift over recent
decades, as the basic currency of understanding shifted from single-neuron tuning towards …
decades, as the basic currency of understanding shifted from single-neuron tuning towards …
Lyapunov spectra of chaotic recurrent neural networks
This article is part of the Physical Review Research collection titled Physics of
Neuroscience. Recurrent networks are widely used as models of biological neural circuits …
Neuroscience. Recurrent networks are widely used as models of biological neural circuits …
Hippocampome. org 2.0 is a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits
Hippocampome. org is a mature open-access knowledge base of the rodent hippocampal
formation focusing on neuron types and their properties. Previously, Hippocampome. org v1 …
formation focusing on neuron types and their properties. Previously, Hippocampome. org v1 …
Rethinking the network determinants of motor disability in Parkinson's disease
For roughly the last 30 years, the notion that striatal dopamine (DA) depletion was the critical
determinant of network pathophysiology underlying the motor symptoms of Parkinson's …
determinant of network pathophysiology underlying the motor symptoms of Parkinson's …
Mind in vitro platforms: versatile, scalable, robust, and open solutions to interfacing with living neurons
X Zhang, Z Dou, SH Kim, G Upadhyay… - Advanced …, 2024 - Wiley Online Library
Motivated by the unexplored potential of in vitro neural systems for computing and by the
corresponding need of versatile, scalable interfaces for multimodal interaction, an accurate …
corresponding need of versatile, scalable interfaces for multimodal interaction, an accurate …
Simple decoding of behavior from a complicated neural manifold
Decoders for brain-computer interfaces (BCIs) assume constraints on neural activity, chosen
to reflect scientific beliefs while yielding tractable computations. We document how low …
to reflect scientific beliefs while yielding tractable computations. We document how low …
Control Principles of Neural Dynamics Revealed by the Neurobiology of Timing
Cognition unfolds dynamically over flexible timescales. A major goal of the field is to
understand the computational and neurobiological principles that enable this flexibility …
understand the computational and neurobiological principles that enable this flexibility …
Representation of a perceptual bias in the prefrontal cortex
Perception is influenced by sensory stimulation, prior knowledge, and contextual cues,
which collectively contribute to the emergence of perceptual biases. However, the precise …
which collectively contribute to the emergence of perceptual biases. However, the precise …