Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …

Tea cream, produced by interactions among tea ingredients, is undesirable in tea beverage
industry. The interaction between bovine serum albumin (BSA) and theaflavin-3, 3 …

In the current investigation, fifteen novel imidazole-pyridine-based molecules were
synthesized and tested against cell lines of the lung (H1299) and colon (HCT116) …

During recent years, small molecules containing five-member heterocyclic moieties have
become the subject of considerable growing interest for designing new antitumor agents …

In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …

Abstract A new series of 1, 3, 4-thiadiazolo-adamantane derivatives were synthesized
through molecular hybridization approach, then used as starting material to synthesize …

Four azoimine quinoline derivatives namely (1Z)-N'-(4-fluorophenyl)-2-oxo-N-quinolin-8-
ylpropanehydrazonamide (H 2 LF),(1Z)-2-oxo-N′-phenyl-N-quinolin-8-ylpropane …

The global microbial resistance is a serious threat to human health, and multitargeting
compounds are considered to be promising to combat microbial resistance. In this work, a …

Abstract In the current study, 5-(pyridin-2-yl)-1, 3, 4-thiadiazol-2-amine (1) was synthesized
via one step reaction of picolinic acid with thiosemicarbazide in the presence of POCl 3 …