Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides: Focus Review

KA Morgan, SE Rudd, A Noor, PS Donnelly - Chemical Reviews, 2023 - ACS Publications
Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Radiolabeled nanomaterial for cancer diagnostics and therapeutics: Principles and concepts

M Goel, Y Mackeyev, S Krishnan - Cancer Nanotechnology, 2023 - Springer
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …

[HTML][HTML] The salivary glands as a dose limiting organ of PSMA-targeted radionuclide therapy: A review of the lessons learnt so far

N Heynickx, K Herrmann, K Vermeulen… - Nuclear medicine and …, 2021 - Elsevier
At present, prostate cancer remains the second most occurring cancer in men, in Europe.
Treatment efficacy for therapy of advanced metastatic disease, and metastatic castration …

Targeted radionuclide therapy of prostate cancer—from basic research to clinical perspectives

M Czerwińska, A Bilewicz, M Kruszewski… - Molecules, 2020 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men and the second
leading cause of cancer-related deaths in Western civilization. Although localized prostate …

Targeting PSMA by radioligands in non-prostate disease—current status and future perspectives

P Backhaus, B Noto, N Avramovic, LS Grubert… - European journal of …, 2018 - Springer
Background Prostate-specific membrane antigen (PSMA) is the up-and-coming target for
molecular imaging of prostate cancer. Despite its name, non-prostate-related PSMA …

[HTML][HTML] The chemical scaffold of theranostic radiopharmaceuticals: radionuclide, bifunctional chelator, and pharmacokinetics modifying linker

HA Holik, FM Ibrahim, AA Elaine, BD Putra, A Achmad… - Molecules, 2022 - mdpi.com
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as
a result of the growing research interest in personalized medicine to improve diagnostic …

[HTML][HTML] Radiometals in imaging and therapy: highlighting two decades of research

S Sharma, MK Pandey - Pharmaceuticals, 2023 - mdpi.com
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

Recent advances and impending challenges for the radiopharmaceutical sciences in oncology

SE Lapi, PJH Scott, AM Scott, AD Windhorst… - The Lancet …, 2024 - thelancet.com
This paper is the first of a Series on theranostics that summarises the current landscape of
the radiopharmaceutical sciences as they pertain to oncology. In this Series paper, we …

Nanoparticles for targeted cancer radiotherapy

RM Pallares, RJ Abergel - Nano Research, 2020 - Springer
Radiotherapy, where ionizing radiation is locally delivered either through an external beam
or by surgically implanting radionuclide-based seeds in the tumor, is one of the gold …