Abstract Withania somnifera (L.) Dunal (Solanaceae) has been used as a traditional
Rasayana herb for a long time. Traditional uses of this plant indicate its ameliorative …

Heat shock proteins (HSPs) constitute a large family of proteins involved in protein folding
and maturation whose expression is induced by heat shock or other stressors. The major …

The heat shock response is an evolutionarily conserved mechanism that protects cells or
organisms from the harmful effects of various stressors such as heat, chemicals toxins, UV …

Oxidative stress is a normal phenomenon in the body. Under normal conditions, the
physiologically important intracellular levels of reactive oxygen species (ROS) are …

Heat shock protein 90 (Hsp90) is a molecular chaperone involved in the maturation of a
plethora of substrates (“clients”), including protein kinases, transcription factors, and E3 …

Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Ethnopharmacological relevance Withania somnifera (L.) Dunal, commonly known as
Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and …

Hsp90 is one of the most important chaperones involved in regulating the maturation of
more than 300 client proteins, many of which are closely associated with refractory diseases …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

The increasing global prevalence of obesity and its associated disorders points to an urgent
need for the development of novel and effective therapeutic strategies that induce healthy …