microRNAs (miRNAs) are small noncoding RNAs that play important roles in
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …

The modulation of gene expression by small non-coding RNAs is a recently discovered level
of gene regulation in animals and plants. In particular, microRNAs (miRNAs) and Piwi …

MicroRNAs have been implicated in regulating diverse cellular pathways. Although there is
emerging evidence that some microRNAs can function as oncogenes or tumour …

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200
megabases and contains at least 30,907 genes. The high gene count is a consequence of …

Non-coding RNAs (ncRNAs) are emerging as key regulators of embryogenesis. They control
embryonic gene expression by several means, ranging from microRNA-induced …

A class of small, non-coding transcripts called microRNAs (miRNAs) that provide a crucial
and pervasive layer of post-transcriptional gene regulation has recently emerged and …

Animal development is an extremely robust process resulting in stereotyped outcomes.
Canalization is a design principle wherein developmental pathways are stabilized to …

Hox genes encode a family of transcriptional regulators that elicit distinct developmental
programmes along the head-to-tail axis of animals. The specific regional functions of …

During microRNA (miRNA) biogenesis, one strand of a∼ 21–22-nucleotide RNA duplex is
preferentially selected for entry into a silencing complex. The other strand, known as the …

Non-protein-coding sequences increasingly dominate the genomes of multicellular
organisms as their complexity increases, in contrast to protein-coding genes, which remain …