This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …

An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

The prevalence of obesity has increased globally over the last 2 decades. Although the body
mass index has been a convenient and simple index of obesity at the population level …

Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans. Several
risk factors promote AF, among which diabetes mellitus has emerged as one of the most …

Epidemiologic and clinical data from the last 2 decades have shown that the prevalence of
heart failure in diabetes is very high, and the prognosis for patients with heart failure is …

Purpose: Studies on long-term sustainability of low-carbohydrate approaches to treat
diabetes are limited. We previously reported the effectiveness of a novel digitally-monitored …

A growing body of evidence is pointing out the pathophysiological role of fat accumulation in
different organs. Ectopic fat depots within heart, liver, skeletal muscle, kidney, and pancreas …

Objectives Obesity is a risk factor for type 2 diabetes mellitus. Among obesity, visceral fat
obesity, and ectopic fat obesity, it has been unclear which has the greatest effect on incident …