Skin color disorders can be caused by various factors, such as excessive exposure to
sunlight, aging and hormonal imbalance during pregnancy, or taking some medications …

Kojic acid presents a variety of applications for human use, especially as a depigmenting
agent. Its derivatives are also proposed in order to prevent chemical degradation, prevent …

Cell viability and cytotoxicity assays play a crucial role in drug screening and evaluating the
cytotoxic effects of various chemicals. The quantification of cell viability and proliferation …

Macrophages are innate immune cells that possess unique abilities to polarize toward
different phenotypes. Classically activated macrophages are known to have major roles in …

Filamentous fungi produce a variety of secondary metabolites of diverse beneficial and
detrimental activities to humankind. The genes required for a given secondary metabolite …

The filamentous fungus Aspergillus oryzae (A. oryzae) has been extensively used for the
biosynthesis of numerous secondary metabolites with significant applications in agriculture …

In the agricultural sector, citrus is one of the most important fruit genus in the world. In this
scenario, Brazil is the largest producer of oranges; 34% of the global production, and …

Aspergillus flavus is a well-known pathogenic fungus for both crops and human beings. The
acquisition of resistance to azoles by A. flavus is leading to more failures occurring in the …

Kojic acid (KA), produced mainly by Aspergillus species, is a product of fungal secondary
metabolism and has great potential in biotechnological applications. The use of KA has …

Kojic acid and deferiprone are iron chelators used for skin lightening and iron‐overload
treatment, respectively. As iron chelation and free radical scavenging are principal factors for …