Global positioning system: understanding long noncoding RNAs through subcellular localization

J Carlevaro-Fita, R Johnson - Molecular cell, 2019 - cell.com
The localization of long noncoding RNAs (lncRNAs) within the cell is the primary
determinant of their molecular functions. LncRNAs are often thought of as chromatin …

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

S Mishra, SS Verma, V Rai, N Awasthee… - Cellular and Molecular …, 2019 - Springer
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

LncATLAS database for subcellular localization of long noncoding RNAs

D Mas-Ponte, J Carlevaro-Fita, E Palumbo, TH Pulido… - Rna, 2017 - rnajournal.cshlp.org
The subcellular localization of long noncoding RNAs (lncRNAs) holds valuable clues to their
molecular function. However, measuring localization of newly discovered lncRNAs involves …

A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury

K Yang, L Zeng, A Ge, S Wang, J Zeng, X Yuan… - Frontiers in …, 2022 - frontiersin.org
Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest
mortality and disability rate of cardiovascular disease. Current studies have shown that …

The role of LncRNAs in translation

D Karakas, B Ozpolat - Non-coding RNA, 2021 - mdpi.com
Long non-coding RNAs (lncRNAs), a group of non-protein coding RNAs with lengths of
more than 200 nucleotides, exert their effects by binding to DNA, mRNA, microRNA, and …

Mechanisms of long noncoding RNA nuclear retention

CJ Guo, G Xu, LL Chen - Trends in biochemical sciences, 2020 - cell.com
Long noncoding RNAs (lncRNAs) are crucial regulators in diverse cellular contexts and
biological processes. The subcellular localization of lncRNAs determines their modes of …

Role of long non-coding RNAs (lncRNAs) in cancer: from subcellular localization to nanoparticles (NPs)-mediated targeted regulation

C Wei, Y Xu, Q Shen, R Li, X **ao, PE Saw… - … Therapy-Nucleic Acids, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Long noncoding RNA and protein abundance in lncRNPs

M Wu, LZ Yang, LL Chen - Rna, 2021 - rnajournal.cshlp.org
Although long noncoding RNAs (lncRNAs) are generally expressed at low levels, emerging
evidence has revealed that many play important roles in gene regulation by a variety of …

Translation of noncoding RNAs: Focus on lncRNAs, pri-miRNAs, and circRNAs

LJ Li, RX Leng, YG Fan, HF Pan, DQ Ye - Experimental cell research, 2017 - Elsevier
Mammalian genome is pervasively transcribed, producing large number of noncoding RNAs
(ncRNAs), including long noncoding RNAs (lncRNAs), primary miRNAs (pri-miRNA), and …

LncRNAs in cancer: from garbage to junk

M Aprile, V Katopodi, E Leucci, V Costa - Cancers, 2020 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNAs) are generally defined as transcripts
longer than 200 nucleotides and not coding for proteins. This review provides an overview of …