Proteomics technologies for cancer liquid biopsies
Alterations in DNAs could not reveal what happened in proteins. The accumulated
alterations of DNAs would change the manifestation of proteins. Therefore, as is the case in …
alterations of DNAs would change the manifestation of proteins. Therefore, as is the case in …
Src: coordinating metabolism in cancer
Metabolism must be tightly regulated to fulfil the dynamic requirements of cancer cells during
proliferation, migration, stemness and differentiation. Src is a node of several signals …
proliferation, migration, stemness and differentiation. Src is a node of several signals …
Pan-cancer analyses reveal genomic features of FOXM1 overexpression in cancer
FOXM1 is frequently overexpressed in cancer, but this has not been studied in a
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …
comprehensive manner. We utilized genotype-tissue expression (GTEx) normal and The …
[HTML][HTML] Pan-cancer profiles of the cuproptosis gene set
H Liu - American journal of cancer research, 2022 - ncbi.nlm.nih.gov
A recent study has revealed a novel cell death pathway, called “cuproptosis”, a programmed
cell death based on copper. A total of 12 genes were involved in the cuproptosis pathway …
cell death based on copper. A total of 12 genes were involved in the cuproptosis pathway …
Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas
Temozolomide (TMZ) is a standard treatment for glioblastoma (GBM) patients. However,
TMZ has moderate therapeutic effects due to chemoresistance of GBM cells through less …
TMZ has moderate therapeutic effects due to chemoresistance of GBM cells through less …
Comprehensive review of web servers and bioinformatics tools for cancer prognosis analysis
H Zheng, G Zhang, L Zhang, Q Wang, H Li… - Frontiers in …, 2020 - frontiersin.org
Prognostic biomarkers are of great significance to predict the outcome of patients with
cancer, to guide the clinical treatments, to elucidate tumorigenesis mechanisms, and offer …
cancer, to guide the clinical treatments, to elucidate tumorigenesis mechanisms, and offer …
Integration of online omics-data resources for cancer research
The manifestations of cancerous phenotypes necessitate alterations at different levels of
information-flow from genome to proteome. The molecular alterations at different information …
information-flow from genome to proteome. The molecular alterations at different information …
E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer
Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing
to~ 5% of all human cancers including almost all cases of cervical cancer and a growing …
to~ 5% of all human cancers including almost all cases of cervical cancer and a growing …
A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies
Abstract The Cancer Genome Atlas (TCGA) and the Cancer Cell Line Encyclopedia (CCLE)
are foundational resources in cancer research, providing extensive molecular and …
are foundational resources in cancer research, providing extensive molecular and …
Integration of transcriptomics, proteomics, and metabolomics data to reveal HER2-associated metabolic heterogeneity in gastric cancer with response to …
Q Yuan, D Deng, C Pan, J Ren, T Wei, Z Wu… - Frontiers in …, 2022 - frontiersin.org
Background Currently available prognostic tools and focused therapeutic methods result in
unsatisfactory treatment of gastric cancer (GC). A deeper understanding of human epidermal …
unsatisfactory treatment of gastric cancer (GC). A deeper understanding of human epidermal …