With 296 million cases estimated worldwide, chronic hepatitis B virus (HBV) infection is the
most common risk factor for hepatocellular carcinoma (HCC). HBV-encoded oncogene X …

Cells are equipped with mechanisms that allow them to rapidly detect and respond to
viruses. These defense mechanisms rely partly on receptors that monitor the cytosol for the …

Background & Aims Hepatitis B virus (HBV) has developed strategies to evade immune
responses. However, the mechanisms involved remain unclear. The NLRP3 inflammasome …

Abstract Knowledge of the immunological events necessary to control hepatitis B virus
(HBV) infection has accelerated in recent years, but their translation towards therapeutic …

Chronic hepatitis B virus (HBV) infection remains a major health burden worldwide for which
there is still no effective curative treatment. Interferon (IFN) consists of a group of cytokines …

Hepatitis B virus (HBV) chronically infects 250 million people worldwide, resulting in nearly
one million deaths annually. Studies in recent years have significantly improved our …

Hepatitis B virus (HBV) infection acquired in adult life is generally self‐limited while chronic
persistence of the virus is the prevalent outcome when infection is acquired perinatally. Both …

The zinc finger antiviral protein (ZAP) is a mammalian host restriction factor that inhibits the
replication of a variety of RNA viruses, including retroviruses, alphaviruses and filoviruses …

Peroxisomes and mitochondria are ubiquitous, highly dynamic organelles with an oxidative
type of metabolism in eukaryotic cells. Over the years, substantial evidence has been …

Hepatitis B virus (HBV) infects hepatocytes specifically and causes immune‐mediated liver
damage. How HBV interacts with the innate immunity at the early phase of infection, either …