The establishment of tandem mass spectrometric fingerprints of phytosterols and tocopherols and the development of targeted profiling strategies in vegetable oils

K Jiang, G Gachumi, A Poudel, B Shurmer… - Journal of the …, 2019 - ACS Publications
Phytosterols and tocopherols are essential for plant biochemistry, and they possess
beneficial health effects for humans. Evaluating the tandem mass spectrometric (MS/MS) …

Cellular uptake and distribution of gemini surfactant nanoparticles used as gene delivery agents

W **, M Al-Dulaymi, I Badea, SC Leary, J Rehman… - The AAPS journal, 2019 - Springer
Gemini surfactants are promising molecules utilized as non-viral gene delivery vectors.
However, little is known about their cellular uptake and distribution after they release their …

Tandem mass spectrometric analysis of novel caffeine scaffold‐based bifunctional compounds for Parkinson's disease

CK Nwabufo, A El‐Aneed… - Rapid communications in …, 2019 - Wiley Online Library
Rationale Novel bifunctional compounds composed of a caffeine scaffold attached to
nicotine (C8‐6‐N), 1‐aminoindan (C8‐6‐I), or caffeine (C8‐6‐C8) were designed as …

The development of simple flow injection analysis tandem mass spectrometric methods for the cutaneous determination of peptide-modified cationic gemini …

M Al-Dulaymi, D Michel, JM Chitanda, I Badea… - … of pharmaceutical and …, 2018 - Elsevier
Diquaternary ammonium gemini surfactants are a class of non-viral gene delivery vectors,
primarily studied for their dermal applications. However, their biological fate has rarely been …

Tandem mass spectrometric analysis of novel peptide‐modified gemini surfactants used as gene delivery vectors

M Al‐Dulaymi, A El‐Aneed - Journal of Mass Spectrometry, 2017 - Wiley Online Library
Diquaternary ammonium gemini surfactants have emerged as effective gene delivery
vectors. A novel series of 11 peptide‐modified compounds was synthesized, showing …

The determination of gemini surfactants used as gene delivery agents in cellular matrix using validated tandem mass spectrometric method

W **, I Badea, SC Leary, A El-Aneed - Journal of pharmaceutical and …, 2019 - Elsevier
A simple, reliable flow injection analysis (FIA)-tandem mass spectrometric (MS/MS) method
was developed for the determination of gemini surfactants, designated as 16-3-16, 16 (Py)-S …

[PDF][PDF] MASS SPECTROMETRIC ANALYSIS OF PHYTOSTEROLS AND TOCOPHEROLS IN PLANT OILS

K Jiang - 2021 - harvest.usask.ca
Phytosterols and tocopherols are bioactives that have numerous health claims. Seeds, oils,
legumes, cereals, and nuts are the main sources of phytosterols and tocopherols. Daily …

[PDF][PDF] ASSESSMENT OF THE BEHAVIOR OF GEMINI SURFACTANT NANOPARTICLES WITHIN BIOLOGICAL SYSTEMS USING MASS SPECTROMETRY

W ** - 2020 - harvest.usask.ca
Gemini surfactants are a class of lipid molecules that have been successfully used in vitro
and in vivo as non-viral gene delivery vectors. However, the biological behavior of gemini …

[PDF][PDF] ROLE OF RGDSK HELICAL ROSETTE NANOTUBES (RGDSK-HRNs) IN INTESTINAL MUCOSAL IMMUNE RESPONSE TO E. COLI INFECTION

NPK Le - 2020 - harvest.usask.ca
Integrin αvβ3 is a transmembrane receptor recognizing arginine-glycine-aspartic acid (RGD)
tripeptide. However, the expression and functions of integrin αvβ3 in intestinal epithelium in …

[PDF][PDF] Preclinical Development of Novel Bifunctional Compounds for Parkinson's Disease

CK Nwabufo - 2019 - harvest.usask.ca
The development of disease-modifying drugs and differential diagnostic agents is a current
focus of research in Parkinson's disease (PD) and one putative target is alpha-synuclein …