Multiple sclerosis: clinical aspects

J Oh, A Vidal-Jordana, X Montalban - Current opinion in …, 2018 - journals.lww.com
A number of recent advances have been made in the clinical diagnosis and prognostication
of multiple sclerosis patients. Future research will enable the development of more accurate …

Implications of gut microbiota in neurodegenerative diseases

H Zhang, Y Chen, Z Wang, G **e, M Liu… - Frontiers in …, 2022 - frontiersin.org
The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …

The genetics of multiple sclerosis: from 0 to 200 in 50 years

SE Baranzini, JR Oksenberg - Trends in genetics, 2017 - cell.com
Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …

The gut microbiota in multiple sclerosis: an overview of clinical trials

G Schepici, S Silvestro, P Bramanti… - Cell …, 2019 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating, and degenerative disease
that affects the central nervous system. A recent study showed that interaction between the …

[HTML][HTML] Diet, gut microbiota, and vitamins D+ A in multiple sclerosis

P Riccio, R Rossano - Neurotherapeutics, 2018 - Elsevier
Central to the understanding of the relationships between diet, gut microbiota, and vitamins
D and A in multiple sclerosis is low-grade inflammation, which is involved in all chronic …

Treatment optimization in multiple sclerosis: Canadian MS working group recommendations

MS Freedman, V Devonshire, P Duquette… - Canadian Journal of …, 2020 - cambridge.org
The Canadian Multiple Sclerosis Working Group has updated its treatment optimization
recommendations (TORs) on the optimal use of disease-modifying therapies for patients …

Diversity of reactive astrogliosis in CNS pathology: heterogeneity or plasticity?

AJ Moulson, JW Squair, RJM Franklin… - Frontiers in cellular …, 2021 - frontiersin.org
Astrocytes are essential for the development and homeostatic maintenance of the central
nervous system (CNS). They are also critical players in the CNS injury response during …

Prevalence of multiple sclerosis (MS) in Iran: a systematic review and meta-analysis

O Mirmosayyeb, V Shaygannejad, S Bagherieh… - Neurological …, 2022 - Springer
Background Prevalence of multiple sclerosis (MS) is increasing world-wide. Iran is not
exception. As the prevalence reported differently in various provinces, we designed this …

Systematic review and meta-analysis of the association between Epstein–Barr virus, multiple sclerosis and other risk factors

BM Jacobs, G Giovannoni, J Cuzick… - Multiple sclerosis …, 2020 - journals.sagepub.com
Background: Epstein–Barr virus (EBV) infection is thought to play a central role in the
development of multiple sclerosis (MS). If causal, it represents a target for interventions to …

An update on vitamin D and disease activity in multiple sclerosis

J Smolders, Ø Torkildsen, W Camu, T Holmøy - CNS drugs, 2019 - Springer
Vitamin D and its main active metabolite 1, 25-dihydroxyvitamin D serve a crucial role in
maintenance of a healthy calcium metabolism, yet have additional roles in immune and …