The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

As an antioxidant, lycopene has acquired importance as it prevents autoxidation of fats and
related products. Tomatoes are an important agricultural product that is a great source of …

Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Abstract Introduction The protein Klotho (KL) was first discovered in KL-deficient mice, which
developed a syndrome similar to premature aging in humans. Since then, KL has been …

Excitation–transcription coupling (E–TC) links synaptic and cellular activity to nuclear gene
transcription. It is generally accepted that E–TC makes a crucial contribution to learning and …

Neurodegenerative diseases (NDDs) are leading causes of death and morbidity in the
elderly worldwide. From the mechanistic/pathological view, oxidative stress, inflammation …

Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …

Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Early and progressive dysfunctions of the dopaminergic system from the Ventral Tegmental
Area (VTA) have been described in Alzheimer's Disease (AD). During the long pre …

Processing and composition can significantly affect the mechanobiology, biodegradability,
and cellular behavior of polymer-based bone scaffolds to replace damaged bone tissue. In …