Covering: 2013. Previous review: Nat. Prod. Rep., 2014, 31, 160–258 This review covers the
literature published in 2013 for marine natural products (MNPs), with 982 citations (644 for …

Aquatic invertebrates are a major source of biomaterials and bioactive natural products that
can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling …

The peer-reviewed marine pharmacology literature from 2012 to 2013 was systematically
reviewed, consistent with the 1998–2011 reviews of this series. Marine pharmacology …

Three‐dimensional (3D) structures have been used to explore the evolution of proteins for
decades, yet they have rarely been utilized to study the molecular evolution of peptides …

Disulfide constrained peptides (DCPs) show great potential as templates for drug discovery.
They are characterized by conserved cysteine residues that form intramolecular disulfide …

A fast quantum-mechanical approach, density-functional tight-binding combined with the
fragment molecular orbital method and periodic boundary conditions, is used to optimize …

A new peptide, gombamide A (1), was isolated from the marine sponge Clathria
gombawuiensis, collected from Korean waters. On the basis of the results of combined …

We describe the discovery and structure of an undecapeptide natural product from a marine
sponge, termed halichondamide A, that is morphed into a fused bicyclic ring topology via …

Tyrosyl-DNA phosphodiesterase 1 (TDP1) is a molecular target for the sensitization of
cancer cells to the FDA-approved topoisomerase inhibitors topotecan and irinotecan. High …

Investigation of the sponge Clathria basilana collected in Indonesia afforded five new
peptides, including microcionamides C (1) and D (2), gombamides B (4), C (5), and D (6) …