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[HTML][HTML] DNA methylation: a historical perspective
AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
In 1925, 5-methylcytosine was first reported in bacteria. However, its biological importance
was not intuitive for several decades. After this initial lag, the ubiquitous presence of this …
was not intuitive for several decades. After this initial lag, the ubiquitous presence of this …
Cis-regulatory sequences in plants: Their importance, discovery, and future challenges
The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …
function to coordinate responses to developmental and environmental cues is of paramount …
DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development
L He, H Huang, M Bradai, C Zhao, Y You, J Ma… - Nature …, 2022 - nature.com
A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …
maintenance of genome integrity is uncontested; however, our understanding of the extent …
Gene body methylation in cancer: molecular mechanisms and clinical applications
Q Wang, F ** studies on crops suggest that agronomic traits can be controlled by gene–
distal intergenic loci. Despite the biological importance and the potential agronomic utility of …
distal intergenic loci. Despite the biological importance and the potential agronomic utility of …
Cistrome and epicistrome features shape the regulatory DNA landscape
The cistrome is the complete set of transcription factor (TF) binding sites (cis-elements) in an
organism, while an epicistrome incorporates tissue-specific DNA chemical modifications and …
organism, while an epicistrome incorporates tissue-specific DNA chemical modifications and …
Dynamics of DNA methylation and its functions in plant growth and development
S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …
regulation of gene expression and genome stability. Chemical modification of DNA base …
[HTML][HTML] Epigenomic diversity in a global collection of Arabidopsis thaliana accessions
The epigenome orchestrates genome accessibility, functionality, and three-dimensional
structure. Because epigenetic variation can impact transcription and thus phenotypes, it may …
structure. Because epigenetic variation can impact transcription and thus phenotypes, it may …