Extracellular neuritic plaques composed of amyloid‑β (Aβ) protein and intracellular
neurofibrillary tangles containing phosphorylated tau protein are the two hallmark proteins of …

Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …

The British Association for Psychopharmacology developed an evidence-based consensus
guideline on the management of catatonia. A group of international experts from a wide …

Acting now on dementia prevention, intervention, and care will vastly improve living and
dying for individuals with dementia and their families, and in doing so, will transform the …

Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

Background: Mild cognitive impairment (MCI) is an important stage between the normal
cognitive decline of aging and dementia. The aim of this study was to compare and …

Objectives: To review available evidence of pharmacological and non-pharmacological
treatment for MCI and analyse information and limitations in national and international …

Agitation is a behavioral syndrome characterized by increased, often undirected, motor
activity, restlessness, aggressiveness, and emotional distress. According to several …

The rising of global geriatric population has contributed to increased prevalence of
dementia. Dementia is a neurodegenerative disease, which is characterized by progressive …

Background Memantine is a moderate affinity uncompetitive antagonist of glutamate NMDA
receptors. It is licensed for use in moderate and severe Alzheimer's disease (AD); in the …