Obesity, exceptionally prevalent in the USA, promotes the incidence and progression of
numerous cancer types including breast cancer. Complex, interacting metabolic and …

Purpose To summarize the evidence of an association between obesity and breast cancer
prognosis. Methods We reviewed the literature regarding overweight and obesity and breast …

Immune exclusion predicts poor patient outcomes in multiple malignancies, including triple-
negative breast cancer (TNBC). The extracellular matrix (ECM) contributes to immune …

Sirtuins are stress‐responsive proteins that direct various post‐translational modifications
(PTM s) and as a result, are considered to be master regulators of several cellular …

Background The role of dietary restriction regimens such as caloric restriction, ketogenic diet
and intermittent fasting in development of cancers has been detected via abundant …

Obesity is associated with a range of health outcomes that are of clinical and public health
significance, including cancer. Herein, we summarize epidemiologic and preclinical …

Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

Purpose The current review shows evidence for the role of adipokines in breast cancer (BC)
pathogenesis summarizing the mechanisms underlying the association between adipokines …

Despite great advances in treatment, cancer remains a leading cause of death worldwide.
Diet can greatly impact health, while caloric restriction and fasting have putative benefits for …

Utilizing targeted therapies capable of reducing cancer metastasis, targeting chemoresistant
and self-renewing cancer stem cells, and augmenting the efficacy of systemic …