Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …

Long non-coding RNAs (lncRNAs) outnumber protein-coding transcripts, but their functions
remain largely unknown. In this Review, we discuss the emerging roles of lncRNAs in the …

Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …

Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …

Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …

Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Gene regulation requires the dynamic coordination of hundreds of regulatory factors at
precise genomic and RNA targets. Although many regulatory factors have specific affinity for …

A diverse catalog of long noncoding RNAs (lncRNAs), which lack protein-coding potential,
are transcribed from the mammalian genome. They are emerging as important regulators in …

Long non-coding RNAs (lncRNAs) are diverse transcription products emanating from
thousands of loci in mammalian genomes. Cis-acting lncRNAs, which constitute a …

Spatiotemporal gene expression programmes are orchestrated by transcriptional
enhancers, which are key regulatory DNA elements that engage in physical contacts with …