Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

C Wischke, SP Schwendeman - International Journal of pharmaceutics, 2008 - Elsevier
Injectable biodegradable and biocompatible copolymers of lactic and glycolic acid (PLGA)
are an important advanced delivery system for week-to-month controlled release of …

Nanoparticles synthesis using supercritical fluid technology–towards biomedical applications

K Byrappa, S Ohara, T Adschiri - Advanced drug delivery reviews, 2008 - Elsevier
Supercritical fluid (SCF) technology has become an important tool of materials processing in
the last two decades. Supercritical CO2 and H2O are extensively being used in the …

[HTML][HTML] Supercritical antisolvent process for pharmaceutical applications: A review

P Franco, I De Marco - Processes, 2020 - mdpi.com
The supercritical antisolvent (SAS) technique has been widely employed in the biomedical
field, including drug delivery, to obtain drug particles or polymer-based systems of …

Methods to Assess in Vitro Drug Release from Injectable Polymeric Particulate Systems

SS D'Souza, PP DeLuca - Pharmaceutical research, 2006 - Springer
This review provides a compilation of the methods used to study real-time (37° C) drug
release from parenteral microparticulate drug delivery systems administered via the …

Subconjunctival nano-and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression

UB Kompella, N Bandi… - … ophthalmology & visual …, 2003 - iovs.arvojournals.org
purpose. The purpose of this study was to determine whether budesonide inhibits
expression of vascular endothelial growth factor (VEGF) in a retinal pigment epithelial cell …

Preparation and optimization of poly (lactic acid) nanoparticles loaded with fisetin to improve anti-cancer therapy

C Feng, X Yuan, K Chu, H Zhang, W Ji, M Rui - International journal of …, 2019 - Elsevier
Fisetin is a natural flavonoid with promising antitumor activity, whereas its clinical application
is limited by its hydrophobic property. In this study, we aimed to load fisetin into poly (lactic …

Supercritical fluids processing of polymers for pharmaceutical and medical applications

E Reverchon, R Adami, S Cardea… - The Journal of …, 2009 - Elsevier
A critical analysis is presented of the supercritical fluids based technologies that have been
proposed in polymer processing for pharmaceutical and medical applications. The formation …

Production of micro-and nano-composite particles by supercritical carbon dioxide

M Bahrami, S Ranjbarian - The Journal of supercritical fluids, 2007 - Elsevier
Carbon dioxide is the only fluid which has been applied in producing composite particles by
supercritical fluid methods. In the present paper, design of composite particles by …

Spherical microparticles production by supercritical antisolvent precipitation: interpretation of results

E Reverchon, R Adami, G Caputo, I De Marco - The Journal of supercritical …, 2008 - Elsevier
Supercritical antisolvent micronization has been the subject of many works aimed at the
production of precipitates with controlled particle size and morphology. Several …

Development of pH-and time-dependent oral microparticles to optimize budesonide delivery to ileum and colon

Y Krishnamachari, P Madan, S Lin - International journal of pharmaceutics, 2007 - Elsevier
A microparticulate system consisting of non-enzymatically degrading poly (dl-lactide-co-
glycolide)(PLGA) core and delivering budesonide site specifically to distal ileum and colon …