Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

JM Bolivar, JM Woodley… - Chemical Society …, 2022 - pubs.rsc.org
Enzyme immobilization has been develo** since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …

The E factor at 30: a passion for pollution prevention

RA Sheldon - Green Chemistry, 2023 - pubs.rsc.org
The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

[HTML][HTML] Chitosan: An overview of its properties and applications

I Aranaz, AR Alcántara, MC Civera, C Arias, B Elorza… - Polymers, 2021 - mdpi.com
Chitosan has garnered much interest due to its properties and possible applications. Every
year the number of publications and patents based on this polymer increase. Chitosan …

Biocatalysis making waves in organic chemistry

U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

Enzyme entrapment, biocatalyst immobilization without covalent attachment

HT Imam, PC Marr, AC Marr - Green Chemistry, 2021 - pubs.rsc.org
In entrapment an active species, which is often a catalyst, is trapped within a material by a
solid or gel forming event; thus, it becomes dispersed within the solid or semi-solid matrix …

[HTML][HTML] Industrial applications of immobilized enzymes—A review

A Basso, S Serban - Molecular Catalysis, 2019 - Elsevier
The use of immobilized enzymes is now a routine process for the manufacture of many
industrial products in the pharmaceutical, chemical and food industry. Some enzymes, such …

Biocatalytic reductive aminations with NAD (P) H-dependent enzymes: enzyme discovery, engineering and synthetic applications

B Yuan, D Yang, G Qu, NJ Turner, Z Sun - Chemical Society Reviews, 2024 - pubs.rsc.org
Chiral amines are pivotal building blocks for the pharmaceutical industry. Asymmetric
reductive amination is one of the most efficient and atom economic methodologies for the …

A perspective on continuous flow chemistry in the pharmaceutical industry

M Baumann, TS Moody, M Smyth… - … Process Research & …, 2020 - ACS Publications
Continuous flow manufacture is an innovative technology platform, which is gaining
momentum within the pharmaceutical industry. The key advantages of continuous flow …

Parameters necessary to define an immobilized enzyme preparation

J Boudrant, JM Woodley, R Fernandez-Lafuente - Process Biochemistry, 2020 - Elsevier
Biocatalytic processes continue to find increasing application in industry. Therefore enzyme
immobilization has also become of increasing importance as a means of allowing enzyme …

Expanding the synthetic toolbox through metal–enzyme cascade reactions

S González-Granda, J Albarrán-Velo… - Chemical …, 2023 - ACS Publications
The combination of metal-, photo-, enzyme-, and/or organocatalysis provides multiple
synthetic solutions, especially when the creation of chiral centers is involved. Historically …