Hidden codes in mRNA: Control of gene expression by m6A
S Murakami, SR Jaffrey - Molecular cell, 2022 - cell.com
Information in mRNA has largely been thought to be confined to its nucleotide sequence.
However, the advent of map** techniques to detect modified nucleotides has revealed …
However, the advent of map** techniques to detect modified nucleotides has revealed …
The role of m6A modification in physiology and disease
C Yang, Y Hu, B Zhou, Y Bao, Z Li, C Gong… - Cell death & …, 2020 - nature.com
Similar to DNA epigenetic modifications, multiple reversible chemical modifications on RNAs
have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (m6A) …
have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (m6A) …
Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI
C Liu, H Sun, Y Yi, W Shen, K Li, Y ** from nanopore direct RNA sequencing
Abstract N6-methyladenosine (m6A) has been increasingly recognized as a new and
important regulator of gene expression. To date, transcriptome-wide m6A detection primarily …
important regulator of gene expression. To date, transcriptome-wide m6A detection primarily …
The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
Glioblastoma is a universally lethal cancer driven by glioblastoma stem cells (GSC). Here,
we interrogated N 6-methyladenosine (m6A) mRNA modifications in GSCs by methyl RNA …
we interrogated N 6-methyladenosine (m6A) mRNA modifications in GSCs by methyl RNA …
Detection of m6A from direct RNA sequencing using a multiple instance learning framework
RNA modifications such as m6A methylation form an additional layer of complexity in the
transcriptome. Nanopore direct RNA sequencing can capture this information in the raw …
transcriptome. Nanopore direct RNA sequencing can capture this information in the raw …