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Lipid vesicle-based molecular robots
A molecular robot, which is a system comprised of one or more molecular machines and
computers, can execute sophisticated tasks in many fields that span from nanomedicine to …
computers, can execute sophisticated tasks in many fields that span from nanomedicine to …
Co-transcriptional production of programmable RNA condensates and synthetic organelles
Condensation of RNA and proteins is central to cellular functions, and the ability to program
it would be valuable in synthetic biology and synthetic cell science. Here we introduce a …
it would be valuable in synthetic biology and synthetic cell science. Here we introduce a …
Synthetic Immunology—Building Immunity from the Bottom‐Up with Synthetic Cells
O Staufer - Advanced NanoBiomed Research, 2024 - Wiley Online Library
Synthetic cells can advance immunotherapy, offering innovative approaches to
understanding and enhancing immune responses. This review article delves into the …
understanding and enhancing immune responses. This review article delves into the …
Sculpting DNA-based synthetic cells through phase separation and phase-targeted activity
Synthetic cells, like their biological counterparts, require internal compartments with distinct
chemical and physical properties where different functionalities can be localized. Inspired by …
chemical and physical properties where different functionalities can be localized. Inspired by …
Interrogation of RNA-protein interaction dynamics in bacterial growth
Characterising RNA–protein interaction dynamics is fundamental to understand how
bacteria respond to their environment. In this study, we have analysed the dynamics of 91 …
bacteria respond to their environment. In this study, we have analysed the dynamics of 91 …
Enzyme-Responsive DNA Condensates
Membrane-less compartments and organelles are widely acknowledged for their role in
regulating cellular processes, and there is an urgent need to harness their full potential as …
regulating cellular processes, and there is an urgent need to harness their full potential as …
Protocell Communication through the Eyes of Synthetic Organic Chemists
A Rebasa‐Vallverdu, S Valente… - European Journal of …, 2023 - Wiley Online Library
The bottom‐up fabrication of synthetic cells (protocells) from molecules and materials, is a
major challenge of modern chemistry. A significant breakthrough has been the engineering …
major challenge of modern chemistry. A significant breakthrough has been the engineering …
Preprint Highlight: A synthetic signaling network imitating the action of immune cells in response to bacterial metabolism
JA De Lora - Molecular Biology of the Cell, 2023 - molbiolcell.org
Synthetic cells, built using approaches from bottom-up synthetic biology, aim to mimic
biological functions of their natural counterparts. However, engineering multilevel …
biological functions of their natural counterparts. However, engineering multilevel …