Background It is now understood that it is the quality rather than the absolute amount of
adipose tissue that confers risk for obesity-associated disease. Adipose-derived stem cells …

According to the developmental origin of health and disease concept, the risk of many age-
related diseases is not only determined by genetic and adult lifestyle factors but also by …

Obesity is frequently associated with impairments in the social domain, and stress at puberty
can lead to long-lasting changes in visceral fat deposition and in social behaviors. However …

White adipose tissue (WAT) distribution is sex dependent. Adipocyte hyperplasia contributes
to WAT distribution in mice driven by cues in the tissue microenvironment, with females …

White adipose tissue (WAT) mass is determined by adipocyte size and number. While
adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT …

Objective Metabolomics may unravel global metabolic changes in response to
environmental exposures and identify important biological pathways involved in the …

House mice, like many tetrapods, produce multielement calls consisting of individual
vocalizations repeated in rhythmic series. In this study, we examine the multielement …

Adult white adipose tissue (WAT) harbors distinct mesenchymal stromal cell subpopulations
that differentially affect WAT function and plasticity. Here we unveil the cellular landscape of …

Puberty is associated with transient insulin resistance that normally recedes at the end of
puberty; however, in overweight children, insulin resistance persists, leading to an increased …

An adverse nutritional environment during the perinatal period increases the risk of adult-
onset metabolic diseases, such as obesity, which may persist across generations. Adipose …