Mitochondrial mass and quality are tightly regulated by two essential and opposing
mechanisms, mitochondrial biogenesis (mitobiogenesis) and mitophagy, in response to …

Cardiovascular disease (CVD) is a serious public health risk, and prevention and treatment
efforts are urgently needed. Effective preventive and therapeutic programs for …

Elevated levels of plasma-free fatty acids and oxidative stress have been identified as
putative primary pathogenic factors in endothelial dysfunction etiology, though their roles are …

Retinal pigment epithelial cell and neuroretinal damage in age-related macular
degeneration (AMD) can lead to serious visual impairments and blindness. Studies have …

Excess dietary intake of saturated fatty acids (SFAs) induces glucose intolerance and
metabolic disorders. In contrast, unsaturated fatty acids (UFAs) elicit beneficial effects on …

Abstract Microcystin-LR (MC-LR), a prevalent cyanotoxin present in hazardous
cyanobacterial blooms, is recognized as a neurotoxic environmental pollutant that induces …

Sterol regulatory element-binding protein 2 (SREBP2) is considered to be a major regulator
to control cholesterol homoeostasis in mammals. However, the role of SREBP2 in teleost …

Protein S-palmitoylation is the process by which a palmitoyl fatty acid is attached to a
cysteine residue of a protein via a thioester bond. A range of methodologies are available for …

This study aimed to explore the critical role of FUNDC1 on epithelial cells in model of
asthma. Patients with asthma and normal healthy volunteers were obtained from our …

Background The current observational studies have disputed the relationship between
various fatty acids and atherosclerotic diseases, and the causal relationship between the …