Dopamine (DA) transmission is governed by processes that regulate release from axonal
boutons in the forebrain and the somatodendritic compartment in midbrain, and by …

Placebos are indispensable controls in randomized clinical trials (RCTs), and placebo
responses significantly contribute to routine clinical outcomes. Recent neurophysiological …

This review updates the existing knowledge suggesting a role for the D3 receptor in
schizophrenia and drug addiction. The D3 receptor is expressed in brain regions controlling …

Adenosine plays a very significant role in modulating striatal glutamatergic and
dopaminergic neurotransmission. In the present essay we first review the extensive …

Drug dependence is a chronic, relapsing disorder in which compulsive drug-seeking and
drug-taking behaviours persist despite serious negative consequences. Addictive …

We characterized undifferentiated (UN) and three differentiation conditions of the SH-SY5Y
neuroblastoma cell line for phenotypic markers of dopaminergic cells, sensitivity to the …

This chapter is an update on the dopamine (DA) imbalance in schizophrenia, including the
evidence for subcortical hyperstimulation of D2 receptors underlying positive symptoms and …

The role of the D3 receptor has remained largely elusive before the development of
selective research tools, such as selective radioligands, antibodies, various highly specific …

The D 2 and D 3 receptors (D 2 R and D 3 R), which are potential targets for antipsychotic
drugs, have a similar structural architecture and signaling pathway. Furthermore, in some …

Tobacco smoking causes high rates of mortality and morbidity throughout the world. Despite
the availability of smoking-cessation medications, maintenance of long-term abstinence is …