STAT3: a target to enhance antitumor immune response
H Lee, SK Pal, K Reckamp, RA Figlin, H Yu - Cancer Immunology and …, 2010 - Springer
Signal transducer and activator of transcription 3 (Stat3) has emerged as a critical regulator
for tumor-associated inflammation. Activation of Stat3 negatively regulates the Th1-type …
for tumor-associated inflammation. Activation of Stat3 negatively regulates the Th1-type …
IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells
Interleukin 4 (IL-4) can suppress delayed-type hypersensitivity reactions (DTHRs), including
organ-specific autoimmune diseases in mice and humans. Despite the broadly documented …
organ-specific autoimmune diseases in mice and humans. Despite the broadly documented …
A brief review of clinical trials involving manipulation of invariant NKT cells as a promising approach in future cancer therapies
M Waldowska, A Bojarska-Junak… - Central European Journal …, 2017 - termedia.pl
In the recent years researchers have put a lot of emphasis on the possible
immunotherapeutic strategies able to target tumors. Many studies have proven that the key …
immunotherapeutic strategies able to target tumors. Many studies have proven that the key …
Co-delivery of tumor-derived exosomes with alpha-galactosylceramide on dendritic cell-based immunotherapy for glioblastoma
Dendritic cell (DC) vaccine–based immunotherapy for glioblastoma multiforme (GBM) has
shown apparent benefit in animal experiments and early-phase clinical trials, but the …
shown apparent benefit in animal experiments and early-phase clinical trials, but the …
Cellular adjuvant properties, direct cytotoxicity of re-differentiated Vα24 invariant NKT-like cells from human induced pluripotent stem cells
S Kitayama, R Zhang, TY Liu, N Ueda, S Iriguchi… - Stem cell reports, 2016 - cell.com
Vα24 invariant natural killer T (iNKT) cells are a subset of T lymphocytes implicated in the
regulation of broad immune responses. They recognize lipid antigens presented by CD1d …
regulation of broad immune responses. They recognize lipid antigens presented by CD1d …
Epinephrine-primed murine bone marrow-derived dendritic cells facilitate production of IL-17A and IL-4 but not IFN-γ by CD4+ T cells
BJ Kim, HP Jones - Brain, behavior, and immunity, 2010 - Elsevier
Sympathetic activation leading to the release of epinephrine and norepinephrine, is known
as an important regulatory circuit related to immune-mediated diseases. However, questions …
as an important regulatory circuit related to immune-mediated diseases. However, questions …
Bisphenol A in combination with TNF-α selectively induces Th2 cell-promoting dendritic cells in vitro with an estrogen-like activity
H Guo, T Liu, Y Uemura, S Jiao, D Wang… - Cellular & molecular …, 2010 - nature.com
Bisphenol A (BPA) is a monomer used in manufacturing a wide range of chemical products,
including epoxy resins and polycarbonate. BPA, an important endocrine disrupting chemical …
including epoxy resins and polycarbonate. BPA, an important endocrine disrupting chemical …
Invariant NKT cells as novel targets for immunotherapy in solid tumors
Natural killer T (NKT) cells are a small population of lymphocytes that possess
characteristics of both innate and adaptive immune cells. They are uniquely poised to …
characteristics of both innate and adaptive immune cells. They are uniquely poised to …
A Comprehensive Ex Vivo Functional Analysis of Human NKT Cells Reveals Production of MIP1-α and MIP1-β, a Lack of IL-17, and a Th1-Bias in Males
JE Snyder-Cappione, C Tincati, IG Eccles-James… - PloS one, 2010 - journals.plos.org
NKT cells contribute to the modulation of immune responses and are believed to be
important in the pathogenesis of autoimmune and infectious diseases, as well as cancer …
important in the pathogenesis of autoimmune and infectious diseases, as well as cancer …
Invariant natural killer T cells regulate anti-tumor immunity by controlling the population of dendritic cells in tumor and draining lymph nodes
Background Invariant natural killer T (iNKT) cells are CD1d-restricted T cells, which respond
rapidly to antigen recognition and promote development of anti-tumor immunity in many …
rapidly to antigen recognition and promote development of anti-tumor immunity in many …