Hydroxamic acids− an intriguing family of enzyme inhibitors and biomedical ligands
CJ Marmion, D Griffith, KB Nolan - European Journal of …, 2004 - Wiley Online Library
This review on hydroxamic acids deals with their efficacy as inhibitors of enzymes including
cyclooxygenases, their synthesis, the complexity and structural diversity of their metal …
cyclooxygenases, their synthesis, the complexity and structural diversity of their metal …
Development of Inhibitors of the 2C-Methyl-d-erythritol 4-Phosphate (MEP) Pathway Enzymes as Potential Anti-Infective Agents
T Masini, AKH Hirsch - Journal of medicinal chemistry, 2014 - ACS Publications
Important pathogens such as Mycobacterium tuberculosis and Plasmodium falciparum, the
causative agents of tuberculosis and malaria, respectively, and plants, utilize the 2 C-methyl …
causative agents of tuberculosis and malaria, respectively, and plants, utilize the 2 C-methyl …
Removal of benzohydroxamic acid-metal complexes pollution from beneficiation wastewater by metal-biochar/peroxymonosulfate system: Behaviors investigation and …
M Li, J Wang, H Shen, Z He, H Zhong, W Sun… - Chemical Engineering …, 2023 - Elsevier
The organometal complexes pollution in beneficiation wastewater has aroused increasing
attentions because they were difficult to remove by traditional technologies. In this study …
attentions because they were difficult to remove by traditional technologies. In this study …
Zinc-dependent deacetylase (HDAC) inhibitors with different zinc binding groups
Y Li, F Wang, X Chen, J Wang, Y Zhao… - Current topics in …, 2019 - ingentaconnect.com
The state of histone acetylation plays a very crucial role in carcinogenesis and its
development by chromatin remodeling and thus altering transcription of oncogenes and …
development by chromatin remodeling and thus altering transcription of oncogenes and …
The design of inhibitors for medicinally relevant metalloproteins
FE Jacobsen, JA Lewis… - … : Chemistry Enabling Drug …, 2007 - Wiley Online Library
A number of metalloproteins are important medicinal targets for conditions ranging from
pathogenic infections to cancer. Many but not all of these metalloproteins contain a zinc (II) …
pathogenic infections to cancer. Many but not all of these metalloproteins contain a zinc (II) …
Oxalic acid drove the permutation decomplexation of the Fe-salicylhydroxamic acid complex and the photocatalytic removal of salicylhydroxamic acid
Y Cao, W Pang, J Yao, Z Li, J Su, W Zhang… - Separation and …, 2024 - Elsevier
Residual salicylhydroxamic acid (SHA) and Fe 3+ in mining sites often form stable, toxic Fe
3+-SHA complexes that are hard to remove and ecologically risky. There's an urgent need …
3+-SHA complexes that are hard to remove and ecologically risky. There's an urgent need …
3-Hydroxypyridin-2-thione as novel zinc binding group for selective histone deacetylase inhibition
Small molecules bearing hydroxamic acid as the zinc binding group (ZBG) have been the
most effective histone deacetylase inhibitors (HDACi) to date. However, concerns about the …
most effective histone deacetylase inhibitors (HDACi) to date. However, concerns about the …
“Tag and modify” protein conjugation with dynamic covalent chemistry
The development of small protein tags that exhibit bioorthogonality, bond stability, and
reversibility, as well as biocompatibility, holds great promise for applications in cellular …
reversibility, as well as biocompatibility, holds great promise for applications in cellular …
QSAR studies on hydroxamic acids: a fascinating family of chemicals with a wide spectrum of activities
SP Gupta - Chemical reviews, 2015 - ACS Publications
Hydroxamic acids constitute a unique family of chemicals with multiple biological activities,
because they act as potent and selective inhibitors of a large number of enzymes, such as …
because they act as potent and selective inhibitors of a large number of enzymes, such as …
Hydroxamic acid–A novel molecule for anticancer therapy
Hydroxamic acid is a potent moiety not only in the field of cancer therapy but also as a
mutagenic agent. Among the various derivatives of hydroxamic acid, SAHA (Suberoylanilide …
mutagenic agent. Among the various derivatives of hydroxamic acid, SAHA (Suberoylanilide …