IgA nephropathy
IgA nephropathy (IgAN), the most prevalent primary glomerulonephritis worldwide, carries a
considerable lifetime risk of kidney failure. Clinical manifestations of IgAN vary from …
considerable lifetime risk of kidney failure. Clinical manifestations of IgAN vary from …
Treatment of IgA nephropathy: a rapidly evolving field
K El Karoui, FC Fervenza… - Journal of the American …, 2024 - journals.lww.com
The pivotal event in the pathophysiology of IgA nephropathy is the binding of circulating IgA-
containing immune complexes to mesangial cells, with secondary glomerular and …
containing immune complexes to mesangial cells, with secondary glomerular and …
[HTML][HTML] The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Uncontrolled complement activation can cause or contribute to glomerular injury in multiple
kidney diseases. Although complement activation plays a causal role in atypical hemolytic …
kidney diseases. Although complement activation plays a causal role in atypical hemolytic …
The treatment of primary IgA nephropathy: change, change, change
DJ Caster, RA Lafayette - American Journal of Kidney Diseases, 2024 - Elsevier
IgA nephropathy (IgAN) is the most common glomerular disease in the world. However, the
approach to treatment remains controversial. There has been an explosion of clinical trials …
approach to treatment remains controversial. There has been an explosion of clinical trials …
IgA nephropathy in adults—treatment standard
PJ Gleeson, MM O'Shaughnessy… - Nephrology Dialysis …, 2023 - academic.oup.com
Immunoglobulin A nephropathy (IgAN) is the most common primary form of glomerular
disease worldwide and carries a high lifetime risk of kidney failure. The underlying …
disease worldwide and carries a high lifetime risk of kidney failure. The underlying …
IgA nephropathy: current understanding and perspectives on pathogenesis and targeted treatment
Y Du, T Cheng, C Liu, T Zhu, C Guo, S Li, X Rao, J Li - Diagnostics, 2023 - mdpi.com
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide, with varied clinical and histopathological features between individuals …
worldwide, with varied clinical and histopathological features between individuals …
KDOQI US commentary on the 2021 KDIGO clinical practice guideline for the management of glomerular diseases
The KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases
represents the first update to this set of recommendations since the initial set of KDIGO …
represents the first update to this set of recommendations since the initial set of KDIGO …
[HTML][HTML] Application of the updated International IgA Nephropathy Prediction Tool in children one or two years post-biopsy
SJ Barbour, R Coppo, L Er, ML Russo, ZH Liu, J Ding… - Kidney International, 2024 - Elsevier
The pediatric International IgA Nephropathy (IgAN) Prediction Tool comprises two models
with and without ethnicity and is the first method to predict the risk of a 30% decline in …
with and without ethnicity and is the first method to predict the risk of a 30% decline in …
Systematic review of the oxford classification of IgA nephropathy: reproducibility and prognostic value
AJ Howie, AD Lalayiannis - Kidney360, 2023 - journals.lww.com
Background The Oxford classification of IgA nephropathy defined five prognostic features
scored subjectively in renal biopsies: mesangial cellularity (M), endocapillary …
scored subjectively in renal biopsies: mesangial cellularity (M), endocapillary …
Novel agents for treating IgA nephropathy
U Kunter, C Seikrit, J Floege - Current Opinion in Nephrology and …, 2023 - journals.lww.com
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