Irisin is a myokine that leads to increased energy expenditure by stimulating the'browning'of
white adipose tissue. In the first description of this hormone, increased levels of circulating …

Irisin is a myokine derived from the cleavage of fibronectin type III domain-containing 5. Irisin
regulates mitochondrial energy, glucose metabolism, fatty acid oxidation, and fat browning …

Irisin is an exercise-induced myokine expressed as a bioactive peptide in multiple tissues
and organs, and exercise and cold exposure are the major inducers for its secretion. Irisin …

Irisin is a hormone-like molecule mainly released by skeletal muscles in response to
exercise. Irisin induces browning of the white adipose tissue and has been shown to …

Heart failure (HF) is a global medical problem that characterizes poor prognosis and high
economic burden for the health system and family of the HF patients. Although modern …

The rising prevalence of chronic diseases such as type 2 diabetes and cardiovascular
diseases owing to fat mass excess has been described. In recent years, muscle …

Irisin, a newly discovered myokine, is considered as a promising candidate for the treatment
of metabolic disturbances and cardiovascular diseases. In the present study, we used two …

Irisin is a novel hormone like polypeptide that is cleaved and secreted by an unknown
protease from fibronectin type III domain-containing protein 5 (FNDC5), a membrane …

Irisin, a myokine released during exercise, promotes browning of subcutaneous adipose
tissue and regulates energy homeostasis. Although exercise constantly reduces blood …

Aging and sedentary life style are considered independent risk factors for many disorders.
Under these conditions, accumulation of dysfunctional and damaged cellular proteins and …