Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
Activatable fluorescent probes for in situ imaging of enzymes
As the main biomarkers of most diseases, enzymes play fundamental but extremely critical
roles in biosystems. High-resolution studies of enzymes using activatable in situ …
roles in biosystems. High-resolution studies of enzymes using activatable in situ …
Coumarin-based near-infrared fluorogenic probes: Recent advances, challenges and future perspectives
Y Fan, Y Wu, J Hou, P Wang, X Peng, G Ge - Coordination Chemistry …, 2023 - Elsevier
Coumarin-based fluorogenic probes have emerged as preferred imaging tools to real-time
and non-invasively monitor target analyte (s) in biological systems, due to their inherent …
and non-invasively monitor target analyte (s) in biological systems, due to their inherent …
Recent advances in small-molecule fluorescent probes for studying ferroptosis
YL Qi, HR Wang, LL Chen, YT Duan… - Chemical Society …, 2022 - pubs.rsc.org
Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …
Small molecular fluorescent probes for the detection of lead, cadmium and mercury ions
SY Chen, Z Li, K Li, XQ Yu - Coordination Chemistry Reviews, 2021 - Elsevier
Heavy-metal pollution, especially Hg 2+, Pb 2+ and Cd 2+, have become a serious issue
worldwide. Exposure to even very low concentrations of these metals will threaten human …
worldwide. Exposure to even very low concentrations of these metals will threaten human …
Rational design of a highly selective near‐infrared two‐photon fluorogenic probe for imaging orthotopic hepatocellular carcinoma chemotherapy
Selective fluorescence imaging of biomarkers in vivo and in situ for evaluating orthotopic
hepatocellular carcinoma (HCC) chemotherapy remains a great challenge due to current …
hepatocellular carcinoma (HCC) chemotherapy remains a great challenge due to current …
Design strategy of fluorescent probes for live drug-induced acute liver injury imaging
Conspectus Drug-induced acute liver injury (DIALI) is increasingly recognized as a
significant cause of acute liver injury (ALI), which is characterized by a rapid loss of …
significant cause of acute liver injury (ALI), which is characterized by a rapid loss of …
Multifunctional self-assembled peptide hydrogels for biomedical applications
Self-assembly is a growth mechanism in nature to apply local interactions forming a
minimum energy structure. Currently, self-assembled materials are considered for …
minimum energy structure. Currently, self-assembled materials are considered for …
Biomarker-activatable probes based on smart AIEgens for fluorescence and optoacoustic imaging
J Ouyang, L Sun, F Zeng, S Wu - Coordination Chemistry Reviews, 2022 - Elsevier
Fluorophores with aggregation-induced emission (AIE) are characterized by many
advantageous features for biomedical applications, including excellent photostability and …
advantageous features for biomedical applications, including excellent photostability and …
Oxygen-dependent regulation of excited-state deactivation process of rational photosensitizer for smart phototherapy
It remains a considerable challenge to realize complete tumor suppression and avoid tumor
regrowth by rational design of photosensitizers (PSs) to improve their photon utilization. In …
regrowth by rational design of photosensitizers (PSs) to improve their photon utilization. In …