Polymers in topical delivery of anti-psoriatic medications and other topical agents in overcoming the barriers of conventional treatment strategies

K Yadav, A Soni, D Singh, MR Singh - Progress in Biomaterials, 2021‏ - Springer
In recent decades, topical treatments to dermal disorders have shown ineffectiveness in
delivering the medication at a particular location without a suitable drug carrier. Psoriasis …

The 'inflammazone'in chronic inflammatory diseases: psoriasis and sarcoidosis

PE Saw, E Song - Trends in Immunology, 2025‏ - cell.com
Chronic inflammatory diseases show significant heterogeneity in their phenotypes, with
diverse immune cells and mediators interacting in response to various stimuli. This review …

TPGS assists the percutaneous administration of curcumin and glycyrrhetinic acid coloaded functionalized ethosomes for the synergistic treatment of psoriasis

T Guo, J Lu, Y Fan, Y Zhang, S Yin, X Sha… - International Journal of …, 2021‏ - Elsevier
Combined therapy with anti-inflammatory drugs is preferred for the topical treatment of
psoriasis, but the codelivery of drugs is restricted due to the lack of a suitable delivery …

A Promising Approach of Dermal Targeting of Antipsoriatic Drugs via Engineered Nanocarriers Drug Delivery Systems for Tackling Psoriasis

D Tripathi, M Srivastava, K Rathour… - Drug Metabolism …, 2023‏ - benthamdirect.com
Psoriasis is a complex autoimmune skin condition with a significant genetic component. It
causes skin inflammation and is characterized by flaky, silvery reddish spots that can worsen …

[HTML][HTML] Skin as an endocrine organ: A narrative review

D Datta, B Madke, A Das - Indian Journal of Dermatology, Venereology …, 2022‏ - ijdvl.com
Skin being the largest organ of the body, is equipped with numerous functional properties.
Over the past few years, intricate research into the biology of skin has led to a gamut of …

Enhanced topical delivery of tacrolimus by a carbomer hydrogel formulation with transcutol P

SG Lee, JB Kang, SR Kim, CJ Kim… - Drug Development …, 2016‏ - Taylor & Francis
Abstract Tacrolimus (TAC), a non-steroidal anti-inflammatory and immunosuppressive
agent, is used for the treatment of atopic dermatitis (AD) and skin immune diseases. TAC …

[HTML][HTML] Lack of galanin receptor 3 alleviates psoriasis by altering vascularization, immune cell infiltration, and cytokine expression

F Sternberg, S Vidali, BS Holub, J Stockinger… - Journal of Investigative …, 2018‏ - Elsevier
The neuropeptide galanin is distributed in the central and peripheral nervous systems and in
non-neuronal peripheral organs, including the skin. Galanin acts via three G protein-coupled …

A promising therapeutic target for psoriasis: Neuropeptides in human skin

Y Zhang, H Zhang, B Jiang, S Yan, J Lu - International …, 2020‏ - Elsevier
Psoriasis is a chronic inflammatory skin disease featured by excessive proliferation of
keratinocytes, clearly defined round erythema and dry, scaly plaques, long-term …

Chemical structure modifications and nano‐technology applications for improving ADME‐Tox properties, a review

F Farouk, R Shamma - Archiv der Pharmazie, 2019‏ - Wiley Online Library
The chemical structure of a drug molecule affects its physicochemical properties and
subsequent biological activities. Many pharmacologically active molecules fail to reach the …

[HTML][HTML] Timed-Release Silica Microcapsules for Consistent Fragrance Release in Topical Formulations

J Yeom, M Kang, A Goh, J Jeon, WS Shim, NG Kang - Applied Sciences, 2024‏ - mdpi.com
Featured Application This study demonstrates a novel use of silica core–shell microcapsules
for timed-release fragrance in topical formulations. The sustained release technology …