Tumors are a heterogeneous group of cell masses originating in various organs or tissues.
The cellular composition of the tumor cell mass interacts in an intricate manner, influenced …

Glioblastoma (GBM) cells are highly heterogeneous and invasive, leading to treatment
resistance and relapse. However, the molecular regulation in and distal to tumors remains …

Background Glioblastoma multiforme (GBM) represents the most prevalent form of primary
malignant tumor within the central nervous system. The emergence of resistance to …

Single-cell technologies enable high-resolution, multi-dimensional analysis of molecular
profiles in cancer biology but face challenges related to low coverage and cell annotation …

Understanding cellular diversity and disease mechanisms requires global analysis of
proteins and their modifications. While next-generation sequencing has advanced our …

It is becoming more broadly accepted that human-based models are needed to better
understand the complexities of the human nervous system and its diseases. The recently …