Importance Primary care clinicians find managing chronic pain challenging. Evidence of
long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious …

Knee osteoarthritis (OA) is a heterogeneous disease associated with substantial effects on
quality of life, and its clinical management is difficult. Among the several available guidelines …

Objective To develop concise, up-to-date, patient-focused, evidence-based, expert
consensus guidelines for the management of knee osteoarthritis (OA), intended to inform …

Abstract Objective To update the American College of Rheumatology (ACR) 2000
recommendations for hip and knee osteoarthritis (OA) and develop new recommendations …

PURPOSE: To develop concise, patient-focussed, up to date, evidence-based, expert
consensus recommendations for the management of hip and knee osteoarthritis (OA), which …

OBJECTIVE: To update evidence for available therapies in the treatment of hip and knee
osteoarthritis (OA) and to examine whether research evidence has changed from 31 …

Background Many patients report symptomatic relief after undergoing arthroscopy of the
knee for osteoarthritis, but it is unclear how the procedure achieves this result. We …

Knee-replacement surgery is frequently done and highly successful. It relieves pain and
improves knee function in people with advanced arthritis of the joint. The most common …

Osteoarthritis (OA) is a degenerative joint disorder commonly encountered in clinical
practice, and is the leading cause of disability in elderly people. Due to the poor self-healing …

Objectives Existing practice guidelines for osteoarthritis (OA) analyze the evidence behind
each proposed treatment but do not prioritize the interventions in a given sequence. The …