Highlights•Various genetically encoded biosensors in microorganisms are
described.•Recent progress in biosensor in the context of metabolic engineering is …

The rapid diversification of synthetic biology tools holds promise in making some classically
hard-to-solve environmental problems tractable. Here we review longstanding problems in …

Abstract Characterization and standardization of inducible transcriptional regulators has
transformed how scientists approach biology by allowing precise and tunable control of …

Living cells can impart materials with advanced functions, such as sense‐and‐respond,
chemical production, toxin remediation, energy generation and storage, self‐destruction …

Abstract Within the Design-Build-Test Cycle for strain engineering, rapid product detection
and selection strategies remain challenging and limit overall throughput. Here we …

Ligand-responsive transcription factors in prokaryotes found simple small molecule-
inducible gene expression systems. These have been extensively used for regulated protein …

Flavonoids represent a diversified family of phenylpropanoid‐derived plant secondary
metabolites. They are widely found in fruits, vegetables, and medicinal herbs. There has …

Controlling gene expression during a bioprocess enables real‐time metabolic control,
coordinated cellular responses, and staging order‐of‐operations. Achieving this with small …

Living cells have evolved to detect and process various signals and can self‐replicate,
presenting an attractive platform for engineering scalable and affordable biosensing …

Nature has evolved exquisite sensing mechanisms to detect cellular and environmental
signals surrounding living organisms. These biosensors have been widely used to sense …