Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Vulvovaginal candidosis

JD Sobel - The Lancet, 2007 - thelancet.com
Despite therapeutic advances, vulvovaginal candidosis remains a common problem
worldwide, affecting all strata of society. Understanding of anti-candida host defence …

Vulvovaginal candidiasis: a current understanding and burning questions

HME Willems, SS Ahmed, J Liu, Z Xu, BM Peters - Journal of Fungi, 2020 - mdpi.com
Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

2018 European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of …

J Sherrard, J Wilson, G Donders… - … journal of STD & …, 2018 - journals.sagepub.com
Four common pathological conditions are associated with vaginal discharge: bacterial
vaginosis, aerobic vaginitis, candidosis, and the sexually transmitted infection …

Candida Infections of the Genitourinary Tract

JM Achkar, BC Fries - Clinical microbiology reviews, 2010 - Am Soc Microbiol
All humans are colonized with Candida species, mostly Candida albicans, yet some develop
diseases due to Candida, among which genitourinary manifestations are extremely …

Zinc prevents vaginal candidiasis by inhibiting expression of an inflammatory fungal protein

E Roselletti, E Pericolini, A Nore, P Takacs… - Science translational …, 2023 - science.org
Candida causes an estimated half-billion cases of vulvovaginal candidiasis (VVC) every
year. VVC is most commonly caused by Candida albicans, which, in this setting, triggers …

[HTML][HTML] Candidalysin: discovery and function in Candida albicans infections

JR Naglik, SL Gaffen, B Hube - Current opinion in microbiology, 2019 - Elsevier
Highlights•Candidalysin is the first peptide toxin identified in any human fungal pathogen.•
Candidalysin is critical for Candida albicans mucosal and systemic infections.•Candidalysin …

Innate and adaptive immunity in female genital tract: cellular responses and interactions

CR Wira, JV Fahey, CL Sentman, PA Pioli… - Immunological …, 2005 - Wiley Online Library
The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …

Recurrent vulvovaginal candidiasis: an immunological perspective

D Rosati, M Bruno, M Jaeger, J Ten Oever, MG Netea - Microorganisms, 2020 - mdpi.com
Vulvovaginal candidiasis (VVC) is a widespread vaginal infection primarily caused by
Candida albicans. VVC affects up to 75% of women of childbearing age once in their life …