Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental
cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with …

Keratin intermediate filament proteins are major cytoskeletal components of the mammalian
simple layered columnar epithelium in the gastrointestinal tract. Human colon crypt epithelial …

In the current study, the surface of superparamagnetic iron oxide (SPION) was coated with
dextran (DEX), and conjugated with folic acid (FA), to enhance the targeted delivery and …

Keratins (KRTs) are the intermediate filament-forming proteins of epithelial cells, classified,
according to their physicochemical properties, into “soft” and “hard” keratins. They have a …

Ovarian cancer is the 8th most common cancer among women and has a 5-year survival of
only 30–50%. While the survival is close to 90% for stage I tumours it is only 20% for stage …

Cancer consists of a group of diseases with the salient properties of an uncontrolled cell
cycle, metastasis, and evasion of the immune response, mainly driven by the genomic …

Background The incidence of bladder cancer (BCa) is approximately four times higher in
men than in women. To develop effective BCa treatments, there is an urgent need to …

The development of resistance by tumor cells to various types of therapy is a significant
problem that decreases the effectiveness of oncology treatments. For more than two …

Metastasis is one of the most urgent issues in breast cancer patients. One of the factors
necessary in the migration process is the remodeling of the extracellular matrix (ECM) …

Breast cancer is a high-risk disease with a high mortality rate among women. Chemotherapy
plays an important role in the treatment of breast cancer. However, chemotherapy eventually …