Single nucleotide polymorphisms (SNPs) are an abundant form of genome variation,
distinguished from rare variations by a requirement for the least abundant allele to have a …

Angiotensin converting enzyme (ACE) plays an essential role in two physiological systems,
one leading to the production of angiotensin II and the other to the degradation of …

Objective To determine whether the genetic prevalence of the CTG expansion in the DMPK
gene associated with myotonic dystrophy type 1 (DM1) in an unbiased cohort is higher than …

Haplotype-based methods offer a powerful approach to disease gene map**, based on
the association between causal mutations and the ancestral haplotypes on which they …

Myotonic dystrophy is part of the group of muscular dystrophies. It is the commonest
inherited muscular dystrophy and has a profound effect on individuals who are diagnosed …

In this review, we focus on the biogeographical distribution of genetic variation and address
whether or not populations cluster according to the popular concept of'race'. We show that …

Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental disorder
that is characterized by several motor and phonic tics. Tics usually develop before 10 years …

Microhaplotype loci (microhaps, MHs) are a novel type of molecular marker of less than 300
nucleotides, defined by two or more closely linked SNPs associated in multiple allelic …

The frequencies of low-activity alleles of glucose-6-phosphate dehydrogenase in humans
are highly correlated with the prevalence of malaria. These “deficiency” alleles are thought …

Abstract Background Both sorghum (Sorghum bicolor) and sugarcane (Saccharum
officinarum) are members of the Andropogoneae tribe in the Poaceae and are each other's …