Bacteria and archaea have evolved defense and regulatory mechanisms to cope with
various environmental stressors, including virus attack. This arsenal has been expanded by …

Twenty years ago, the publication of the first bacterial genome sequence, from Haemophilus
influenzae, shook the world of bacteriology. In this Timeline, we review the first two decades …

Our objective is to provide an optimistic strategy for reversing soil degradation by increasing
public and private research efforts to understand the role of soil biology, particularly …

We describe an algorithm for gene identification in DNA sequences derived from shotgun
sequencing of microbial communities. Accurate ab initio gene prediction in a short …

▪ Abstract Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain
known as lipid A (or endotoxin), a nonrepeating “core” oligosaccharide, and a distal …

Using in silico analysis we studied a novel family of repetitive DNA sequences that is
present among both domains of the prokaryotes (Archaea and Bacteria), but absent from …

Unlike eukaryotes, which evolve principally through the modification of existing genetic
information, bacteria have obtained a significant proportion of their genetic diversity through …

▪ Abstract Most prokaryotic signal-transduction systems and a few eukaryotic pathways use
phosphotransfer schemes involving two conserved components, a histidine protein kinase …

Sequence-directed genetic interference pathways control gene expression and preserve
genome integrity in all kingdoms of life. The importance of such pathways is highlighted by …

The Glimmer system for microbial gene identification finds∼ 97–98% of all genes in a
genome when compared with published annotation. This paper reports on two new …