Long-acting injectable (LAI) formulations can provide several advantages over the more
traditional oral formulation as drug product opportunities. LAI formulations can achieve …

Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …

Nanoemulsions, usually spherical, are a group of dispersed particles used for
pharmaceutical and biomedical aids and vehicles that show great promise for the future of …

In vitro–in vivo correlation (IVIVC) is a predictive mathematical model describing the
relationship between an in vitro property and a relevant in vivo response of drug products …

Rodents remain one of the most widespread and damaging invasive alien species on
islands globally. The current toolbox for insular rodent eradications is reliant on the …

Abstract Herein, entecavir-3-palmitate (EV-P), an ester prodrug of entecavir (EV), was
employed as a model drug, and the effect of drug particle size on in vivo pharmacokinetic …

Simple Summary Drug use is essential to treat diseases in food-producing animals. The
most widely used drugs are antiparasitics and antimicrobials. They contribute to …

The present study aims at elucidating the intricate nature of the drug release and absorption
following intramuscular (im) injection of sustained-release prodrug nanocrystals …

This review article provides an assessment of advantages/limitations of the use of current in
vitro release models to predict in vivo performance of parenteral sustained release products …

Innovations in the field of long-acting injectable drug development are increasingly being
reported. More advanced in vitro and in vivo characterization can improve our …