Formation of propionate and butyrate by the human colonic microbiota

P Louis, HJ Flint - Environmental microbiology, 2017 - Wiley Online Library
The human gut microbiota ferments dietary non‐digestible carbohydrates into short‐chain
fatty acids (SCFA). These microbial products are utilized by the host and propionate and …

Faecalibacterium: a bacterial genus with promising human health applications

R Martín, D Rios-Covian, E Huillet… - FEMS Microbiology …, 2023 - academic.oup.com
In humans, many diseases are associated with alterations in gut microbiota, namely
increases or decreases in the abundance of specific bacterial groups. One example is the …

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

XC Morgan, TL Tickle, H Sokol, D Gevers, KL Devaney… - Genome biology, 2012 - Springer
Background The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis
result from alterations in intestinal microbes and the immune system. However, the precise …

Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders

A Metwaly, S Reitmeier, D Haller - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

The role of the gut microbiota in nutrition and health

HJ Flint, KP Scott, P Louis, SH Duncan - … reviews Gastroenterology & …, 2012 - nature.com
The microbial communities that colonize different regions of the human gut influence many
aspects of health. In the healthy state, they contribute nutrients and energy to the host via the …

Microbial degradation of complex carbohydrates in the gut

HJ Flint, KP Scott, SH Duncan, P Louis, E Forano - Gut microbes, 2012 - Taylor & Francis
Bacteria that colonize the mammalian intestine collectively possess a far larger repertoire of
degradative enzymes and metabolic capabilities than their hosts. Microbial fermentation of …

Early infancy microbial and metabolic alterations affect risk of childhood asthma

MC Arrieta, LT Stiemsma, PA Dimitriu… - Science translational …, 2015 - science.org
Asthma is the most prevalent pediatric chronic disease and affects more than 300 million
people worldwide. Recent evidence in mice has identified a “critical window” early in life …

The first 1000 cultured species of the human gastrointestinal microbiota

M Rajilić-Stojanović, WM De Vos - FEMS microbiology reviews, 2014 - academic.oup.com
The microorganisms that inhabit the human gastrointestinal tract comprise a complex
ecosystem with functions that significantly contribute to our systemic metabolism and have …

The potential of gut commensals in reinforcing intestinal barrier function and alleviating inflammation

K Hiippala, H Jouhten, A Ronkainen, A Hartikainen… - Nutrients, 2018 - mdpi.com
The intestinal microbiota, composed of pro-and anti-inflammatory microbes, has an essential
role in maintaining gut homeostasis and functionality. An overly hygienic lifestyle …

Phylogenetic distribution of three pathways for propionate production within the human gut microbiota

N Reichardt, SH Duncan, P Young… - The ISME …, 2014 - academic.oup.com
Propionate is produced in the human large intestine by microbial fermentation and may help
maintain human health. We have examined the distribution of three different pathways used …