PEGylated lipid nanoparticle formulations: immunological safety and efficiency perspective

R Tenchov, JM Sasso, QA Zhou - Bioconjugate chemistry, 2023 - ACS Publications
Lipid nanoparticles (LNPs) have been recognized as efficient vehicles to transport a large
variety of therapeutics. Currently in the spotlight as important constituents of the COVID-19 …

The challenge and prospect of mRNA therapeutics landscape

Y Weng, C Li, T Yang, B Hu, M Zhang, S Guo… - Biotechnology …, 2020 - Elsevier
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …

Barriers and strategies of cationic liposomes for cancer gene therapy

C Liu, L Zhang, W Zhu, R Guo, H Sun, X Chen… - … Therapy Methods & …, 2020 - cell.com
Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors
for decades with the advantages of excellent biodegradability, biocompatibility, and high …

Rational design of cancer nanomedicine for simultaneous stealth surface and enhanced cellular uptake

Q **, Y Deng, X Chen, J Ji - Acs Nano, 2019 - ACS Publications
Owing to the complex and still not fully understood physiological environment, the
development of traditional nanosized drug delivery systems is very challenging for precision …

Advanced functional polymer materials

K Wang, K Amin, Z An, Z Cai, H Chen… - Materials Chemistry …, 2020 - pubs.rsc.org
The research on advanced functional polymers is being driven by the fast-growing demand
for new functional materials that can be used in revolutionary technologies. Polymers can be …

Tumor acidity activating multifunctional nanoplatform for NIR-mediated multiple enhanced photodynamic and photothermal tumor therapy

J Liu, H Liang, M Li, Z Luo, J Zhang, X Guo, K Cai - Biomaterials, 2018 - Elsevier
The study reports a multifunctional nanoplatform based on mesoporous silica coated gold
nanorod (AuNR@ MSN) to overcome biological barriers associating with nanocarrier for …

Polymeric nanoparticles for drug delivery

JM Chan, PM Valencia, L Zhang, R Langer… - … : Methods and protocols, 2010 - Springer
The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has
shown significant therapeutic potential. Concurrently, targeted delivery technologies are …

Photoactivated polymersome nanomotors: traversing biological barriers

J Shao, S Cao, DS Williams… - Angewandte Chemie …, 2020 - Wiley Online Library
Synthetic nanomotors are appealing delivery vehicles for the dynamic transport of functional
cargo. Their translation toward biological applications is limited owing to the use of non …

Design of nanocarriers based on complex biological barriers in vivo for tumor therapy

J Liu, M Li, Z Luo, L Dai, X Guo, K Cai - Nano Today, 2017 - Elsevier
Nanoscale drug delivery systems (NDDS) have shown great potential in tumor treatment
due to its unique advantages, especially its unique enhanced permeability and retention …

Near-infrared triggered upconversion polymeric nanoparticles based on aggregation-induced emission and mitochondria targeting for photodynamic cancer therapy

Y Guan, H Lu, W Li, Y Zheng, Z Jiang… - ACS applied materials …, 2017 - ACS Publications
Photodynamic therapy (PDT) is an auspicious strategy for cancer therapy by yielding
reactive oxygen species (ROS) under light irradiation. Here, we have developed near …