The importance of circadian biology has rarely been considered in pre-clinical studies, and
even more when translating to the bedside. Circadian biology is becoming a critical factor for …

Light around twilight provides the primary entrainment signal for circadian rhythms. Here we
review the mechanisms and responses of the mouse and human circadian systems to light …

Background Anxiety disorders are the most prevalent mental illnesses in the US and are
estimated to consume one-third of the country's mental health treatment cost. Although …

Except for latitudes close to the equator, seasonal variation in light hours can change
dramatically between summer and winter. Yet investigations into the interplay between …

Gene therapy using recombinant adeno‐associated virus (rAAV) vectors to treat blinding
retinal dystrophies has become clinical reality. Therapeutically impactful targeting of …

To understand how arousal state impacts cerebral hemodynamics and neurovascular
coupling, we monitored neural activity, behavior, and hemodynamic signals in un …

Optogenetic methods provide efficient cell-specific modulations, and the ability of
simultaneous neural activation and inhibition in the same brain region of freely moving …

Breakthroughs in understanding the neural basis of natural behavior require neural
recording and intervention to be paired with high-fidelity multimodal behavioral monitoring …

Over the past two decades, evidence has accumulated that neurogenesis can occur in both
the juvenile and adult mammalian hypothalamus. Levels of hypothalamic neurogenesis can …

We present a miniature head mounted two-photon fiber-coupled microscope (2P-FCM) for
neuronal imaging with active axial focusing enabled using a miniature electrowetting lens …