[HTML][HTML] Cytotoxic urea Schiff base complexes for multidrug discovery as anticancer activity and low in vivo oral assessing toxicity
Novel mononuclear complexes 2–8 derived from hybrid Urea Schiff base HL were
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …
Silver nanoparticle functionalized by glutamine and conjugated with thiosemicarbazide induces apoptosis in colon cancer cell line
H Taati, H Sangani, A Davoudi… - Scientific Reports, 2024 - nature.com
The high mortality rate of colon cancer indicates the insufficient efficacy of current
chemotherapy. Thus, the discussion on engineered metal nanoparticles in the treatment of …
chemotherapy. Thus, the discussion on engineered metal nanoparticles in the treatment of …
Design, synthesis, cytotoxic screening and molecular docking studies of novel hybrid thiosemicarbazone derivatives as anticancer agents
FZ Mohammed, YW Rizzk, IM El Deen… - Chemistry & …, 2021 - Wiley Online Library
Thiosemicarbazones have been the focus of scientists owing to their broad clinical
anticancer range. Herein, A Series of new thiosemicarbazone derivatives 5–9 were …
anticancer range. Herein, A Series of new thiosemicarbazone derivatives 5–9 were …
[HTML][HTML] Oxamic acid thiohydrazides and hydrazones based on them as convenient starting compounds for the synthesis of S-and N-containing heterocyclic products …
MM Krayushkin, VN Yarovenko - Arabian Journal of Chemistry, 2024 - Elsevier
The chemistry of hydrazones is currently undergoing intensive development. For example,
thioacylhydrazones, which are synthesized most often from thiosemicarbazides, have …
thioacylhydrazones, which are synthesized most often from thiosemicarbazides, have …
Versatile Biological Activities of Thiosemicarbazones and Their Metal Complexes
One of the most crucial objectives in medicinal chemistry is the development of innovative
and beneficial bioactive compounds with various biological activities. Thiosemicarbazone …
and beneficial bioactive compounds with various biological activities. Thiosemicarbazone …
Structural elucidation, Hirshfeld surface, DFT, molecular docking and molecular dynamics studies of a novel thiazole derivative as anti-cancer drug
Detailed structural and non-covalent interactions in the novel thiazole derivative benzyl 4-(4-
chlorophenyl) thiazole-2-carboxylate (6a) has been synthesized and characterized by …
chlorophenyl) thiazole-2-carboxylate (6a) has been synthesized and characterized by …
New 1, 3, 4-thiadiazoles derivatives: Synthesis, antiproliferative activity, molecular docking and molecular dynamics
Aim: A series of 1, 3, 4-thiadiazole himachalene hybrids were prepared from the treatment of
a himachalen-4-one thiosemicarbazone derivative with N-aryl-C-ethoxycarbonyl-nitrilimines …
a himachalen-4-one thiosemicarbazone derivative with N-aryl-C-ethoxycarbonyl-nitrilimines …
Anticancer Studies of Newly Synthesized Thiazole Derivatives: Synthesis, Characterization, Biological Activity, and Molecular Docking
Thiazole and its derivatives have received a lot of attention from researchers due to its wide
biological, pharmacological, and anticancer properties. A novel series of 2-[2-[4-Hydroxy-3 …
biological, pharmacological, and anticancer properties. A novel series of 2-[2-[4-Hydroxy-3 …
Cytotoxicity effect of nickel hydroxide nanoparticles functionalized by glutamine and conjugated by thiosemicarbazide on human lung cancer cell line (A549) and …
AA Dehkaei, K Khalatbari, A Emamifar, SM Taramsari… - Gene Reports, 2022 - Elsevier
Lung cancer is the second leading cause of cancer-associated death, worldwide and current
therapeutic approaches have low efficiency in treating metastatic lung cancers …
therapeutic approaches have low efficiency in treating metastatic lung cancers …
Dual PI3K/Akt inhibitors bearing coumarin-thiazolidine pharmacophores as potential apoptosis inducers in MCF-7 cells
Breast cancer is the most common malignancy worldwide; therefore, the development of
new anticancer agents is essential for improved tumor control. By adopting the …
new anticancer agents is essential for improved tumor control. By adopting the …