Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

The goal of this review article is to provide a resource for longitudinal studies, using animal
models, directed at understanding and modifying the relationship between cognition and …

Age-related cognitive decline has been linked to a diverse set of neurobiological
mechanisms, including bidirectional changes in proteins critical for neuron function …

Delay discounting (DD) is a quantifiable psychological phenomenon that regulates decision-
making. Nevertheless, the neural substrates of DD and its relationship with other cognitive …

Individuals engage in the process of risk-based decision making on a daily basis to navigate
various aspects of life. There are, however, individual differences in this form of decision …

The glucocorticoid (GC) hypothesis posits that effects of stress and dysregulated
hypothalamic-pituitary-adrenal axis activity accumulate over the lifespan and contribute to …

Individuals who use cocaine exhibit maladaptive decision-making, overweighting rewards,
and underweighting potential risks. We previously showed that chronic cocaine self …

Glutamate signaling is essential for the persistent neural activity in prefrontal cortex (PFC)
that enables working memory. Metabotropic glutamate receptors (mGluRs) are a diverse …

Impairments in choosing optimally between immediate and delayed rewards are associated
with numerous psychiatric disorders. Such 'intertemporal'choice is influenced by genetic and …

Background: Cannabis (marijuana) is the most widely used illicit drug in the USA, and
consumption among adolescents is rising. Some animal studies show that adolescent …